56430-96-7

Upstream product

• 131-58-8 2-Methylbenzophenone 
• 925-90-6 ethylmagnesium bromide 
• 33872-80-9 o-tolyl magnesium chloride 
• 93-55-0 1-phenyl-propan-1-one 
• 108-86-1 bromobenzene 
• 2040-14-4 2-methylpropiophenone 

Downstream Products

• 4333-82-8 (Z)-1-methyl-2-(1-phenylprop-1-en-1-yl)benzene 

Relevant academic research and scientific papers

Method of treating filariae

The present invention relates to a novel method for treating a mammal suffering from filariae.

Heterocyclic carboxylic acids

Novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent, the compounds thus having the general formula I STR1 wherein Y is STR2 wherein R1 and R2 independently are C3-8 cycloalkyl phenyl or thienyl all of which may be optionally substituted with halogen, trifluoromethyl, C1-16 alkyl or C1-6 alkoxy; s is 1, 2 or 3; x is --CH2 --, --O-- or STR3 -wherein R3 is hydrogen or C1-6 -alkyl; r is 2, 3 or 4; R4 and R5 each represents hydrogen or may together represent a bond and R6 is OH or C1-8 -alkoxy; and pharmaceutically acceptable acid addition salts are potent inhibitors of GABA uptake from the synaptic cleft.

Investigation of Intermediate Radicals in the Grignard Reactions. Rates of Electron Transfer and of Successive R. Transfer to Ketones from Grignard Reagents

In the Grignard reactions with benzil (diketone) and with benzophenone (monoketone) in THF rates of electron transfer and of successive R. transfer from Grignard reagents were determined by direct observations of intermediate radicals.The electron transfer rates from Grignard reagents to ketones are dependent on both the electrochemical properties of Grignard reagents and ketones.

Alpha-substituted benzhydrol derivatives

The invention relates to new α-substituted benzhydrols and pharmaceutically acceptable acid addition salts or quaternary ammonium salts thereof with enzyme promoting or inhibiting effects;

α-Substituted benzhydrol derivatives and a process for the preparation thereof

A compound of the formula: STR1 wherein Z is ethyl or vinyl, R1 and R2 are hydrogen, lower alkyl, lower alkenyl or trihalomethyl, R3 and R4 are hydrogen, lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl or phenyl, and R5 is lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl, or phenyl with the proviso that where R1, R2, R3 and R4 each is hydrogen, R5 is not methyl attached to the 4-position of the benzene ring, or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof is disclosed as effective in the regulation of the liver microsomal enzyme system.