56570-57-1Relevant academic research and scientific papers
Synthetic Route to Enaminones via Metal-Free Four-Component Sequential Reactions of Aryl Olefins with CHCl3, Et3N, and TBHP
Zhang, Jiantao,Zhou, Peng,Yin, Aiguo,Zhang, Shuhua,Liu, Weibing
, p. 8980 - 8986 (2021/06/30)
An efficient and modular strategy was used to obtain enaminones with a wide range of functional groupsviaa four-component sequential reaction. This reaction proceeded under mild conditions without a catalyst in one pot. Furthermore, the products could be transformed into thiadiazoles.
Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols
Ueno, Satoshi,Usui, Kazumi,Kuwano, Ryoichi
supporting information; experimental part, p. 1303 - 1307 (2011/07/08)
A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols. Georg Thieme Verlag Stuttgart · New York.
