56593-17-0Relevant academic research and scientific papers
Mg-promoted reductive coupling of aromatic carbonyl compounds with trimethylsilyl chloride and bis(chlorodimethylsilyl) compounds
Uchida, Tetsuro,Kita, Yoshio,Maekawa, Hirofumi,Nishiguchi, Ikuzo
, p. 3103 - 3111 (2007/10/03)
Mg-promoted reductive coupling of aromatic carbonyl compounds (1) with chlorosilanes, such as trimethylsilyl chloride (TMSCl:2), 1,2- bis(chlorodimethylsilyl)ethane (3) and 1,5-dichlorohexamethyltrisiloxane (4), in N,N-dimethylformamide (DMF) at room temperature brought about selective and facile reductive formation of both of carbon-silicon and oxygen-silicon bonds to give the corresponding α-trimethylsilylalkyl trimethylsilyl ethers (5) and cyclic siloxanes (6), (7) in moderate to good yields, respectively. The present facile and selective coupling may be initiated through electron transfer from Mg metal to aromatic carbonyl compounds (1).
Mg-promoted reductive cross coupling of carbonyl compounds with trimethylsilyl chloride
Ishino, Yoshi,Maekawa, Hirofumi,Takeuchi, Hiroshi,Sukata, Kazuaki,Nishiguchi, Ikuzo
, p. 829 - 830 (2007/10/03)
Mg-promoted cross-coupling of aromatic carbonyl compounds with trimethylsilyl chloride (TMSCl) in DMF at room temperature brought about reductive carbon-silicon bond formation to give the corresponding α-trimethylsilylalkyl trimethylsilyl ethers selectively in good yields.The reaction may be initiated through electron transfer from Mg metal to the carbonyl compounds.
Acetylsilane O-Silylcyanohydrins as Precursors to α-Silyl Ketones and β-Siloxy-N,N-bissilylenamines
Cunico, Robert F.,Kuan, Chia P.
, p. 4634 - 4638 (2007/10/02)
Reduction of acetylsilane O-silylcyanohydrins gave β-amino-α-hydroxysilanes, which were diazotized to give α-silyl ketones.The addition of organolithium reagents to the cyanohydrins was accompanied by sequential C -> N and O -> N silyl group migrations.Silylation of the resulting lithium enolates afforded β-siloxy-N,N-bissilylenamines.
