56637-44-6

Basic information

• Product Name: 1,3-Dithiane, 2-(4-methylphenyl)-
• CAS NO: 56637-44-6
• Molecular Formula: C11H14S2
• Molecular Weight: 210.364
• Mol File: 56637-44-6.mol
• Article Data: 61

Chemical Properties

• Melting Point: 92 °C
• Boiling Point: 344.9±42.0 °C(Predicted)
• Density: 1.131±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,3-Dithiane, 2-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dithiane, 2-(4-methylphenyl)-(56637-44-6)
• EPA Substance Registry System: 1,3-Dithiane, 2-(4-methylphenyl)-(56637-44-6)

Safety Data

• Hazardous Substances Data: 56637-44-6(Hazardous Substances Data)

Usage

Molecular weight

220.37 g/mol

Melting point

85-88°C

Type of compound

Dithiane derivative

Usage

Organic synthesis

Role in organic chemistry

Building block for complex molecules and pharmaceuticals

Reactivity

Formation of carbon-carbon and carbon-sulfur bonds

Additional function

Chiral auxiliary in asymmetric synthesis reactions

Upstream product

• 109-80-8 1.3-propanedithiol 
• 5663-40-1 2-(4-methylphenyl)-1,3-dioxane 
• 2929-93-3 p-tolylmethylenediacetate 
• 138470-21-0 2-p-Tolyl-[1,3]oxathiane 
• 2403-51-2 2-(4-methylphenyl)-1,3-dioxolane 
• 104-87-0 4-methyl-benzaldehyde 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 22391-04-4 2-(4-tolyl)-1,3-oxathiolane 
• 6784-58-3 1-(1,3-dithian-2-ylidene)propan-2-one 
• 110-89-4 piperidine 
• 99-94-5 p-Toluic acid 
• 57529-04-1 2-chloro-1,3-dithiane 
• 67-56-1 methanol 
• 55727-23-6 3‐(1,3-dithiane-2-yl)pentane-2,4-dione 

Downstream Products

• 97684-09-8 1,1,1,7,7,7-Hexaphenyl-2,6-dithiaheptan 
• 104-87-0 4-methyl-benzaldehyde 
• 141118-38-9 2-(p-methylphenyl)-1,3-dithiane-1-oxide 
• 144266-26-2 2-(p-methylphenyl)-1,3-dithiane-1,3-dioxide 
• 111997-77-4 2-(4-Methylphenyl)-1,3-dithian-2-ylium-tribromid 
• 5663-40-1 2-(4-methylphenyl)-1,3-dioxane 
• 98-86-2 acetophenone 
• 68185-94-4 trimethyl-4-methylbenzoylsilane 
• 130552-03-3 Trimethyl-(2-p-tolyl-[1,3]dithian-2-yl)-silane 
• 128155-66-8 2-(4-Methylphenyl)-1,3-bis(trimethylsilyl)propene 
• 128155-66-8 1-Methyl-4-((E)-2-trimethylsilanyl-1-trimethylsilanylmethyl-vinyl)-benzene 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 725270-40-6 2-(4-methyl)phenyl-2-triethylsilyl-1,3-dithiane 

Relevant articles and documents

Synthesis of 3-Amino-4-iodothiophenes through Iodocyclization of 1-(1,3-Dithian-2-yl)propargylamines

1-(1,3-Dithian-2-yl)propargylamines undergo iodo-cylization regioselectively to afford tetrasubstituted 3-amino-4-iodothiophenes in 30–87 % yields by iodide induced cleavage of dithiane ring in a bicyclic sulfonium intermediate. A mechanism for this unprecedented transformation was proposed and tentatively supported by the isolation of an intermediate structure. 1-(1,3-Dithian-2-yl)propargylamines were prepared in 30–94 % yields by Au-catalyzed one-pot, three-component reaction of 1,3-dithiane-2-carbaldehydes, amines, and alkynes so called A3-coupling reaction.

Catalytic application of sulfamic acid-functionalized magnetic Fe3O4nanoparticles (SA-MNPs) for protection of aromatic carbonyl compounds and alcohols: Experimental and theoretical studies

Protection techniques of functional groups within the structure of organic compounds are important synthetic methods against unwanted attacks from various reagents during synthetic sequences. Acetal and thioacetal groups are well known as protective funct

An uncommon use of irradiated flavins: Br?nsted acid catalysis

We present that thioacetalization of aldehydes can be induced by blue light irradiation in the presence of a catalytic amount of riboflavin tetraacetate (RFTA) under aerobic conditions. Several control experiments have suggested that the reaction is more