56660-59-4

Basic information

• Product Name: 2,3-dibroMotetrahydro-2H-pyran
• Synonyms: 2,3-dibroMotetrahydro-2H-pyran;2,3-Dibromo-tetrahydro-pyran
• CAS NO: 56660-59-4
• Molecular Formula: C₅H₈Br₂O
• Molecular Weight: 243.92442
• Mol File: 56660-59-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 224.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.932±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3-dibroMotetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibroMotetrahydro-2H-pyran(56660-59-4)
• EPA Substance Registry System: 2,3-dibroMotetrahydro-2H-pyran(56660-59-4)

Safety Data

• Hazardous Substances Data: 56660-59-4(Hazardous Substances Data)

Usage

General Description

2,3-dibromotetrahydro-2H-pyran is a chemical compound with the molecular formula C5H8Br2O. It is a colorless liquid with a molecular weight of 219.92 g/mol. 2,3-dibroMotetrahydro-2H-pyran is commonly used in organic synthesis as a versatile building block for the preparation of various organic compounds. It is also utilized as a reagent in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. 2,3-dibromotetrahydro-2H-pyran is considered to be a useful intermediate in the production of a wide range of chemical products and is important in the field of organic chemistry.

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 26274-19-1 5-bromo-3,4-dihydro-2H-pyran 
• 56-23-5 tetrachloromethane 
• 128-08-5 N-Bromosuccinimide 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 5324-21-0 3-bromo-2-methoxy-tetrahydropyran 
• 39150-42-0 3-Brom-2-aethoxytetrahydropyran 
• 81991-71-1 3-bromo-2-phenyl-tetrahydro-pyran 
• 1051940-71-6 3-Bromo-tetrahydro-pyran-2-carbonitrile 
• 105499-32-9 (S)-(-)-Tetrahydropyran-2-carboxylic Acid 
• 31518-13-5 3,4-dihydro-2H-pyran-6-carbonitrile 
• 31518-14-6 3,4-dihydro-2H-pyran-6-carboxylic acid 
• 58223-46-4 7-methylnonanal 
• 13047-01-3 3-bromotetrahydro-2H-pyran 
• 156051-16-0 (+/-)-3-bromo-2-methyloxane 
• 31502-21-3 (E)-oct-4-en-1-ol 
• 6559-34-8 6-methoxy-3,6-dihydro-2H-pyran 

Relevant articles and documents

Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids

Spiral binding: A highly enantioselective hydrogenation of unsaturated heterocyclic acids has been developed by using chiral iridium/spirophosphino oxazoline catalysts (see scheme; BArF-=tetrakis[3,5- bis(trifluoromethyl)phenyl]borate, Boc=tert-butoxycarbonyl). This reaction provided an efficient method for the preparation of optically active heterocyclic acids with excellent enantioselectivities. Copyright

SYNTHESIS OF THE RACEMIC PROPIONATE OF 8-METHYL-2-DECANOL, THE SEX HORMONE OF THE SEVERAL LEAF-EATING BUGS Diabrotica (CHRYSOMELIDAE)

A new method has been developed for the synthesis of sex hormone of Diabrotica leaf-eating bugs, namely, the racemic propionate of 8-methyl-2-decanol, from 7-methyl-1-nonanol, which, in turn, was obtained by two methods using the Grignard reaction from furfural and from 2,3-dibromotetrahydropyran.

THE STERIC COURSE OF THE REACTIONS OF 2,3-DIHALOTETRAHYDROPYRANS WITH GRIGNARD REAGENTS

The steric course of some reactions of 2,3-dihalotetrahydropyrans with sodium methoxide and with methyl- and phenyl-magnesium bromides has been reinvestigated.Whereas the methanolysis of the cis- and trans-dichlorides occurs with practically complete inversion, it has been confirmed that their reactions, as well as those of dibromides, with methylmagnesium bromide are non-stereospecific, yielding mixtures of trans- and cis-3-halo-2-methyl-tetrahydropyrans in ratios that are independent of the configurations of the starting dihalides.It has been further established that grignard reagents cause equlibration of cis- and trans-dihalide mixtures in a reaction that is much faster than the Grignard coupling step.