58042-45-8

Basic information

• Product Name: 1-(2,2-diethoxyethoxy)-3-Methylbenzene
• Synonyms: 1-(2,2-diethoxyethoxy)-3-Methylbenzene
• CAS NO: 58042-45-8
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.2961
• EINECS: -0
• Mol File: 58042-45-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2,2-diethoxyethoxy)-3-Methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-diethoxyethoxy)-3-Methylbenzene(58042-45-8)
• EPA Substance Registry System: 1-(2,2-diethoxyethoxy)-3-Methylbenzene(58042-45-8)

Safety Data

• Hazardous Substances Data: 58042-45-8(Hazardous Substances Data)

Usage

General Description

1-(2,2-diethoxyethoxy)-3-Methylbenzene, also known as diethylene glycol monovinyl ether, is a chemical compound with the molecular formula C11H16O3. It is a colorless to pale yellow liquid with a sweet, fruity odor. This chemical is commonly used as a solvent, as well as in the production of resins, paints, and coatings. It also has applications in the manufacture of adhesives, sealants, and inks. Diethylene glycol monovinyl ether is considered to be slightly toxic and may cause irritation to the skin, eyes, and respiratory system. It should be handled with care and used in well-ventilated areas to minimize exposure.

Upstream product

• 108-39-4 3-methyl-phenol 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 3019-89-4 sodium 3-methylphenoxide 

Downstream Products

• 176851-48-2 2-(3-methylphenoxy)acetaldehyde 
• 17059-51-7 6-methyl benzofuran 
• 5670-23-5 4-methyl-benzofuran 
• 96159-61-4 2C₁₀H₁₃N₅O₃*H₂O₄S 
• 41964-07-2 2(1H)-pyrimidinone, 5-(3-methylphenoxy) 
• 53341-46-1 (E)-3-(dimethylamino)-2-(meta-tolyloxy)acrylaldehyde 

Relevant articles and documents

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.

Bronchodilator and Antiulcer Phenoxypyrimidinones

Series of 5-phenoxy-2(1H)-pyrimidinones, 5-phenoxy-4(3H)-pyrimidinones, and related compounds were prepared in a follow-up of a lead prepared as a potential cyclic nucleotide regulating agent.Compounds were evaluated for bronchodilator activity in histamine-challenged guinea pigs and for antiulcer activity in a cold-restraint, stressed rat ulcer model.Bronchodilator activity comparable to, or greater than, that of theophylline was found in both the 2(1H)- and 4(3H)-pyrimidinone series and was most prominent in analogues containing either an electron-withdrawing or -donating substituent in the para position of the phenoxy ring.Significant antiulcer activity was observed only in the 2(1H)-pyrimidinone series among three closely related analogues.One of these, 5-(m-methylphenoxy)-2(1H)-pyrimidinone (3), exhibited more potent antiulcer effects than the clinically useful antiulcer agent carbenoxolone, without demonstrating bronchodilator activity.