56820-34-9

Upstream product

• 124-41-4 sodium methylate 
• 219786-86-4 3-(methoxycarbonyl)-1-methyl-4-phenyl-5-(trichloroacetyl)-1,4-dihydropyridine 
• 96-31-1 N,N'-Dimethylurea 
• 100-52-7 benzaldehyde 
• 922-67-8 propynoic acid methyl ester 
• 4685-10-3 3-(methoxycarbonyl)-1-methylpyridinium iodide 

Relevant academic research and scientific papers

One-pot synthesis of N-substituted 4-aryl-1,4-dihydropyridines under solvent-free conditions and microwave irradiation

The three-component condensation of benzaldehyde derivatives, alkyl propiolates, and primary amines catalyzed by silica gel, zeolite HY, montmorillonite K-10, and acidic alumina under microwave irradiation gave N-substituted 4-aryl-1,4-dihydropyridines in short reaction times and high yields. The best results were obtained with silica gel.

Synthesis of 3-5-diacyl-4-phenyl-1,4-dihydropyridines

3,5-Diacyl-4-phenyl-1,4-dihydropyridines have been synthesized via a regio- and chemoselective addition of Ph2Cu(CN)Li2 to β-substituted N- alkylpyridinium salts, followed by acylation of the intermediate 1,4- dihydropyridines with t