56862-39-6

Basic information

• Product Name: Benzenemethanamine, N-(2-chloro-2-propenyl)-N-methyl-
• CAS NO: 56862-39-6
• Molecular Formula: C11H14ClN
• Molecular Weight: 195.692
• Mol File: 56862-39-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(2-chloro-2-propenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(2-chloro-2-propenyl)-N-methyl-(56862-39-6)
• EPA Substance Registry System: Benzenemethanamine, N-(2-chloro-2-propenyl)-N-methyl-(56862-39-6)

Safety Data

• Hazardous Substances Data: 56862-39-6(Hazardous Substances Data)

Upstream product

• 685891-48-9 1-benzyl-3-chloroazetidine 
• 100-46-9 benzylamine 
• 111043-42-6 N-benzyl-3-(trimethylsilyloxy)azetidine 
• 111043-32-4 1-benzyl-(3-chloro-2-trimethylsilyloxypropyl)-amine 
• 54881-13-9 N-benzyl-3-hydroxyazetidine 
• 75605-52-6 N-benzyl-3-amino-1-chloropropan-2-ol 
• 78-88-6 2,3-Dichloroprop-1-ene 
• 103-67-3 benzyl-methyl-amine 

Relevant articles and documents

New Synthesis of Propargylic Amines from 2-(Bromomethyl)aziridines. Intermediacy of 3-Bromoazetidinium Salts

A new, efficient, and straightforward synthesis provides propargylamines in high overall yields (64-77%) by transformation of 1-(arylmethyl)-2-(bromomethyl)aziridines into N,N-di(arylmethyl)N-(2-propynyl)amines via N-(2,3-dibromopropyl)amines and N-(2-bromo-2-propenyl)amines. The conversion of N-(2,3-dibromopropyl)amines into N-(2-bromo-2-propenyl)amines is based on a novel analogue of the Hofmann elimination. A Yamaguchi-Hirao alkylation, a Sonogashira coupling, or a hydroarylation reaction further functionalized these propargylamines toward potentially interesting compounds for medicinal and agrochemical use.