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2H-1-Benzopyran,3,4-dihydro-6-methyl-2-phenyl-(9CI), also known as 6-Methyl-2-phenyl-3,4-dihydro-2H-1-benzopyran, is a chemical compound with the molecular formula C16H16O. It belongs to the class of organic compounds known as chromans, which are derivatives of benzopyran. This specific compound features a benzopyran ring system with a methyl group at the 6-position and a phenyl group at the 2-position. It is an important intermediate in the synthesis of various pharmaceuticals and natural products, particularly those with potential therapeutic applications. The compound's structure and properties make it a valuable building block in organic synthesis, allowing for the creation of a wide range of complex molecules.

5689-37-2

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5689-37-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5689-37-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,8 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5689-37:
(6*5)+(5*6)+(4*8)+(3*9)+(2*3)+(1*7)=132
132 % 10 = 2
So 5689-37-2 is a valid CAS Registry Number.

5689-37-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-methyl-2-phenyl-chroman

1.2 Other means of identification

Product number -
Other names 6-Methylflavan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5689-37-2 SDS

5689-37-2Relevant academic research and scientific papers

One step synthesis of 2-alkenylchromanes via inverse electron-demand Hetero-Diels–Alder reaction of o-quinone methide with unactivated dienes

Liu, Jian,Wang, Xiaoxiao,Xu, Lubin,Hao, Zhihui,Wang, Liang,Xiao, Jian

supporting information, p. 7642 - 7649 (2016/11/11)

The synthetically important 2-alkenylchromane derivatives were constructed in good yields under metal-free condition via inverse electron demand Hetero-Diels–Alder reaction of o-quinone methides with unactivated dienes. This strategy features mild conditi

Tosylhydrazine mediated conjugate reduction and sequential reductive coupling cyclization: Synthesis of 2-arylchromans

Shang, Xuyang,Zhou, Xiaomeng,Zhang, Wei,Wan, Changfeng,Chen, Junmin

supporting information, p. 8187 - 8193 (2015/12/30)

Tosylhydrazine mediated conjugate reduction of 2-hydroxyl chalcones and sequential reductive coupling cyclization is described. This is an unprecedented protocol and an extremely efficient method for a one-pot domino synthesis of 2-arylchromans in good to excellent yields from commercially available, cheap starting materials. More importantly, the two-step reactions can be easily controlled to afford dihydrochalcones or 2-arylchromans by the mole amounts of tosylhydrazine. Furthermore, the operational simplicity of the process and the high functional group tolerance are remarkable.

Synthesis of chromans via [3 + 3] cyclocoupling of phenols with allylic alcohols using a Mo/o-chloranil catalyst system

Yamamoto, Yoshihiko,Itonaga, Kouhei

supporting information; experimental part, p. 717 - 720 (2009/08/19)

(Chemical Equation Presented) The combination of a molybdenum complex (CpMoCl(CO)3 or [CpMo(CO)3]2) and o-chloranil was used as a catalyst in the [3 + 3] cyclocoupling of phenols and allylic alcohols under microwave heating conditions. Substituted chromans were selectively obtained in moderate to good isolated yields.

Intramolecular excited-state interactions in phenol-styrene bicromophoric systems: A photochemical and photophysical study

Consuelo Jiménez,Miranda, Miguel A,Tormos, Rosa

, p. 115 - 120 (2007/10/03)

The intramolecular excited state interaction between phenol and styrene in a series of trans-2-cinnamylphenols bearing electron-donating substituents at the phenolic ring has been directly observed as an exciplex emission in acetonitrile. The photochemica

An improved method for synthesis of 1-benzopyrans from unsaturated alcohols and phenols using a catalytic amount of acids

Ishino,Mihara,Hayakawa,Miyata,Kaneko,Miyata

, p. 439 - 448 (2007/10/03)

1-Benzopyrans, such as chromans and chromenes, were prepared in good to excellent yields by using a catalytic amount of p-toluenesulfonic acid through intermolecular cyclization reaction of phenols with unsaturated alcohols in 1,2-dichlroroethane.

STEREOSELECTIVITY AT BENZYLIC CARBON. FLAVANOIDS-V. SYNTHESIS OF TRANS-4-ACETAMIDOFLAVANS

Hirwe, A.,Marathe, K. G.,Mohorkar, S. S.,Ramdas, K.,Singh, C. B.

, p. 1539 - 1546 (2007/10/02)

Some reactions of 4-substituted flavans have been studied. 4-Chloro/bromo derivatives react under neutral conditions with phthalimide and acetonitrile leading to displacement of axial halogen by nitrogen with inversion.In contrast, irrespective of the ste

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