56974-15-3

Upstream product

• 120346-63-6 (E)-3-butyl-2-phenylsulphonyl-2-phenylthiooxirane 
• 3561-67-9 bis(phenylthio)methane 
• 108-98-5 thiophenol 
• 142-62-1 hexanoic acid 
• 931-59-9 benzenesulfenyl chloride 
• 693-02-7 hex-1-yne 
• 120346-59-0 (E)-1-phenylsulphonyl-1-phenylthiohex-1-ene 
• 15296-86-3 1-(phenylsulfanyl)methyl phenyl sulfone 
• 35453-12-4 phenyl phenylthiomethyl sulfoxide 
• 110-62-3 pentanal 
• 142-61-0 Hexanoyl chloride 
• 882-33-7 diphenyldisulfane 
• 120346-78-3 S-phenyl 2-iodo(thiohexanoate) 
• 127894-31-9 1-phenylthio-1-hexyne 

Downstream Products

• 942-92-7 caprophenone 
• 927-49-1 dipentyl ketone 
• 621-15-8 N-(n-hexanoyl)aniline 

Relevant academic research and scientific papers

Beta-lactones as antibacterial agents

The present invention relates to specific beta-lactone compounds and compositions thereof for the treatment of infections, such as, e.g., infections with bacteria or infections with protozoa, in particular infections with Gram-positive and/or Gram-negativ

Synthesis of thiol esters by the reaction of ricinoleic acid with thiols under solvent-free conditions

The synthesis of several ricinoleic acid thiol esters starting from cis-(R)-12-hydroxyoctadec-9-enoic acid and thiols in the presence of N,N'-dicyclohexylcarbodiimide (DCC) is described. The method is efficient for aromatic and aliphatic thiols, selective

β-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes

(Chemical Equation Presented) A chemical proteomic strategy has been applied directly to bacterial proteomes, and b-lactones have been identified as important natural product derivatives with a high affinity to various enzyme classes (see picture). This a

Reductive cleavage of the sulfur-sulfur bond by the samarium/Cp 2TiCI2 used for the synthesis of S-phenyl thiolesters

A mild method is reported for the reductive cleavage of the sulfur-sulfur bond by the samarium/ Cp2TICI2 system to give a phenylthiolate anion species which reacts with acyl chlorides to give the corresponding S-phenyl thiolesters in

Cleavage of S-S bond by Sm/cat. CoCl2 or Sm/cat. CoCl2 · 6H2O system. A novel method for the synthesis of thiolesters

The Sm/cat. CoCl2 or Sm/cat. CoCl2 · 6H2O system promoted dlsulfides to react with anhydrides or acyl chlorides to afford thiolesters in good yields under mild and neutral conditions.

Reductive cleavage of S-S bond in diphenyl disulfide by samarium diiodide: A novel method for the synthesis of thiolesters

Diphenyl disulfide is reduced by samarium diiodide to yield samarium phenylthiolate. This new thiolate anion species mildly reacts with acyl chlorides to give thiolesters in good yields.

Preparation of 2-Halogeno S-Phenyl Thioesters from 2-Phenylsulphonyl-2-phenylthiooxiranes. Crystal Structures of 2-Phenylsulphonyloxiranes

1-Phenylsulphonyl-1-phenylthioalkenes 8 are prepared with high stereoselectivity as (E) isomers in a one-pot process by reaction of phenyl phenylthiomethyl sulphone 9 with aldehydes, followed by elimination.Nucleophilic epoxidation of these alkenes with l

The hydroboration of 1-alkylthio-1-alkynes, and its application to the syntheses of s-alkyl alkanethioates and (Z)-1-alkylthio-1-alkenes

Hydroboration of 1-alkylthio-1-alkynes with dicyclohexylborane or bis(1,2-dimethylpropyl)borane proceeded smoothly, adding most of the dialkylboryl group to the α-position of the triple bond. The resulting alkenylboranes afforded either S-alkyl alkanethio

A HIGHLY EFFICIENT SYNTHETIC ROUTE TO KETONES THROUGH SEQUENTIAL COUPLING REACTIONS OF GRIGNARD REAGENTS WITH S-PHENYL CARBONOCHLORODITHIOATE IN THE PRESENCE OF NICKEL OR IRON CATALYSTS

The sequential coupling reactions of Grignard reagents with S-phenyl carbonochloridothioate in the presence of nickel(II) or iron(III) catalysts provides a very mild and straightforward route to symmetrical and unsymmetrical aliphatic and aromatic ketones.