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57-30-7 Usage

Chemical Properties

Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y7 (2.2.2, Method II).


Different sources of media describe the Uses of 57-30-7 differently. You can refer to the following data:
1. Phenobarbital sodium salt has been used: to anesthetize mice for inducing ischemia-reperfusion injuryas a positive control for the activation of constitutive androstane receptor (CAR)in bioluminescent yeast bioreporters (BLYAS) assay
2. Anticonvulsant; sedative-hypnotic.


ChEBI: A barbiturate that is the sodium salt of phenobarbital (barbituric acid substituted at C-5 by ethyl and phenyl groups).

Brand name

Luminal Sodium (Sterling Winthrop).

General Description

Odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3). Bitter taste. A narcotic.

Air & Water Reactions

Hygroscopic. May be sensitive to prolonged exposure to air. Water soluble. Aqueous solutions are unstable, but may be kept at or below 50°F for a few days.

Reactivity Profile

Phenobarbital sodium can react with strong oxidizing agents. Incompatible with ammonium salts and chloral hydrate. Also incompatible with acids and acidic substances .

Fire Hazard

Flash point data for Phenobarbital sodium are not available; however, Phenobarbital sodium is probably combustible.

Biochem/physiol Actions

Phenobarbital, a substituted barbituric acid is an antileptic drug and is not easily eliminated from circulation. It hyperpolarizes the synaptic neuronal membranes by favoring the activation of neuronal postsynaptic GABAA?receptors by γ aminobutyric acid (GABA). Phenobarbital is also effective in treating neonatal seizures and status epilepticus.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intravenous, intraperitoneal, intraduodenal, and subcutaneous routes. Human systemic effects by ingestion: nausea or vomiting and coma. Experimental reproductive effects. Mutation data reported. Used to treat epilepsy, as a hypnotic and sedative. When heated to decomposition it emits toxic fumes of NOx and NazO. See also BARBITURATES

Check Digit Verification of cas no

The CAS Registry Mumber 57-30-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57-30:
47 % 10 = 7
So 57-30-7 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name phenobarbital sodium

1.2 Other means of identification

Product number -
Other names phenobarbital mono sodium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57-30-7 SDS

57-30-7Relevant articles and documents



Page/Page column 5, (2010/03/02)

Disclosed are new phenobarbital salts, methods of preparation, and uses thereof.

Water dispersion containing ultrafine particles of organic compounds


, (2008/06/13)

A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 μm prepared by the steps of heating the medicine or hormone in a vacuum vessel at a temperature of 30° C. higher than the boiling point and at a pressure between 0.01 Torr and 10 Torr to evaporate the medicine or hormone and condensing the medicine or hormone on a recovery plate to obtain the condensate.