57009-13-9

Usage

Uses

Used in Fragrance Industry:
Methyl 2-(propan-2-yloxy)benzoate is used as a fragrance ingredient for its fruity odor, adding pleasant scents to various personal care and cosmetic products.
Used in Paint and Coating Industry:
Methyl 2-(propan-2-yloxy)benzoate is used as a solvent in paints, varnishes, and lacquers, improving their application and drying properties.
Used in Insect Repellent Industry:
Methyl 2-(propan-2-yloxy)benzoate is used as an insect repellent, providing protection against insects due to its aromatic properties.
Used in Food Industry:
Methyl 2-(propan-2-yloxy)benzoate is used as a flavoring agent in food products, enhancing their taste and aroma.

Upstream product

• 75-30-9 2-iodo-propane 
• 119-36-8 methyl salicylate 
• 75-26-3 isopropyl bromide 
• 67-56-1 methanol 
• 63635-26-7 2-isopropoxybenzoic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 606-45-1 2-methoxybenzoic acid methyl ester 
• 683-60-3 sodium isopropylate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 63920-58-1 2-isopropoxybenzamide 
• 317334-20-6 1-(3-benzylphenyl)-3-(3-isopropoxypyridin-2-yl)-propane-1,3-dione 
• 60638-81-5 5-chlorosulfonyl-2-hydroxy-benzoicacid methylester 
• 63635-26-7 2-isopropoxybenzoic acid 
• 1414813-89-0 3,5-bis(2-isopropoxyphenyl)-1H-pyrazole 
• 1414813-90-3 bis(3,5-bis(2-isopropoxyphenyl)-1H-pyrazol-1-yl)methane 
• 1414813-88-9 1,3-bis(2-isopropoxyphenyl)propane-1,3-dione 

Relevant academic research and scientific papers

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Metal-free Synthesis of Spiro-2,2′-benzo[b]furan-3,3′-ones via PhI(OAc)2-Mediated Cascade Spirocyclization

Treating the benzyl protected 3-hydroxy-1,3-bis(2-hydroxyphenyl)prop-2-en-1-ones solely with PhI(OAc)2 (PIDA) in DCE at room temperature readily furnished the seldom studied spiro-2,2′-benzo[b]furan-3,3′-ones in satisfactory to excellent yields. The hypervalent iodine reagent enables the metal-free cascade spirocyclization resulting in the dual oxidative C?O bond formation. (Figure presented.).

SULPHAMOYLARYL DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF LIVER FIBROSIS

Potent 5-HT2B antagonist of Formula (A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof and their use wherein R1 to R4 and Ar have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them, alone or in combination with other drugs, in fibrosis and/or cirrhosis prevention or therapy.

1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof

Certain 1-(aromatic- or heteroaromatic-substituted-3-(heteroaromatic substituted)-1,3-propanediones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

Facile alkoxyl exchange of 2-methoxybenzoates via nucleophilic aromatic substitution with sodium alkoxides in dimethylformamide

Methyl 2-methoxybenzoate undergoes facile nuclear-methoxyl displacement by treatment with sodium butexide or isopropoxide in dimethylformamide.