57096-03-4

Upstream product

• 186581-53-3 diazomethane 
• 65501-87-3 5,7-dihydroxy-8-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 6601-66-7 6-demethoxytangeretin 
• 6608-33-9 5,4′-hydroxy-7,8-dimethoxyflavone 
• 74-88-4 methyl iodide 
• 1486-51-7 p-(benzyloxy)benzoic acid 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 
• 73909-61-2 4'-hydroxy-5,7,8-trimethoxyflavone 
• 6601-67-8 4'-benzyloxy-5,7,8-trimethoxyflavone 
• 5128-44-9 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 89456-41-7 5,8-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone 
• 77-78-1 dimethyl sulfate 
• 56595-79-0 2-(4'-benzyloxybenzoyloxy)-3,4,6-trimethoxyacetophenone 
• 56595-80-3 2-hydroxy-4'-benzyloxy-3,4,6-trimethoxydibenzoylmethane 

Relevant academic research and scientific papers

Regioselective hydroxylation of 2-hydroxychalcones by dimethyldioxirane towards polymethoxylated flavonoids

The flavone nucleus is part of a large number of natural products and medicinal compounds. In this presentation the novel regioselective hydroxylation of hydroxyarenes with DMD is described. The results showed further that flavonoids with 5-hydroxy group were selectively oxyfunctionalized at the para-position C8 carbon atom by DMD. Finally, according to this methodology, the naturally occurring isosinensetin, tangeretin, sinensetin, nobiletin, natsudaidain, gardenin B, 3,3′,4′,5,6,7,8- heptamethoxyflavone, quercetin and its derivatives were synthesized.

GALANGUSTIN, A NEW FLAVONE FROM GALEOPSIS ANGUSTIFOLIA

Galangustin has the structure of 5,7-dihydroxy-8,4'-dimethoxyflavone.