57128-67-3

Basic information

• Product Name: (+)-tartrate salt of (2S)-2-amino-4-phenylbut-3-ene
• Synonyms: (+)-tartrate salt of (2S)-2-amino-4-phenylbut-3-ene
• CAS NO: 57128-67-3
• Molecular Weight: 279.293
• Mol File: 57128-67-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-tartrate salt of (2S)-2-amino-4-phenylbut-3-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-tartrate salt of (2S)-2-amino-4-phenylbut-3-ene(57128-67-3)
• EPA Substance Registry System: (+)-tartrate salt of (2S)-2-amino-4-phenylbut-3-ene(57128-67-3)

Safety Data

• Hazardous Substances Data: 57128-67-3(Hazardous Substances Data)

Upstream product

• 122-57-6 1-Phenylbut-1-en-3-one 
• 61210-87-5 [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide 
• 87-69-4 L-Tartaric acid 
• 53309-95-8 (+/-)-2-amino-4-phenylbut-3-ene 

Downstream Products

• 95121-83-8 (2S)-N-benzoyl-N-phenyl-2-amino-4-phenylbut-3-ene 
• 51616-91-2 (-)-(S,E)-4-Phenylbut-3-en-2-ylamin 

Relevant articles and documents

Homogeneous Catalysis. Transition-Metal-Catalyzed Claisen Rearrangements

Palladium(0), palladium(II), rhodium(I), and iridium(I) complexes catalyze the rearrangement of allyl imidates to allyl amides under mild conditions.The palladium(II) catalysis is characterized by exclusive regioselectivity and high steroeselectivity whereas the palladium(0), rhodium(I), and iridium(I) catalysts generally give both the and rearrangement products and although the palladium(0) catalyst can give high stereoselectivity, the rhodium(I) and iridium(I) catalysts are nonstereoselective.After a series of experiments using chiral substrates and substrates with specific deuterium labels, the mechanisms of these catalytic reactions have been elucidated.The palladium(II) catalysis is proposed to proceed via cyclic carbonium ion intermediates, and the mechanism resembles the thermal uncatalyzed Claisen rearrangement path.The palladium(0) catalysis is a form of catalytic allylation involving oxidative addition followed by nucleophilic attack on a ?-allyl intermediate.The mechansim of the rhodium(I) and iridium(I) catalysis was not as fully investigated as the others, but it appears to involve carbonium ion intermediates formed by cleavage of the allyl-oxygen bond.