57139-25-0Relevant articles and documents
Isoindolinone synthesis through Rh/Cu-catalyzed oxidative C-H/N-H annulation of N -methoxy benzamides with saturated ketones
Du, Xiao,Hu, Yuntao,Huang, Decai,Wu, Hailong,Yang, Darun,Yang, Wendi,Zhao, Huaiqing
supporting information, p. 783 - 789 (2022/02/03)
The synthesis of isoindolinones from N-methoxy benzamides and saturated ketones via a bimetallic tandem catalytic annulation has been accomplished. The reaction is catalyzed by a Rh/Cu-cocatalytic system and proceeds via the combination of Cu-catalyzed de
Three-Component Synthesis of Isoquinoline Derivatives by a Relay Catalysis with a Single Rhodium(III) Catalyst
Zhou, Chao,Jiang, Jijun,Wang, Jun
supporting information, p. 4971 - 4975 (2019/09/03)
A rhodium(III)-catalyzed one-pot three-component reaction of N-methoxybenzamide, α-diazoester, and alkyne was developed, providing an alternative way to synthesize isoquinoline derivatives. Mechanistically, it is a relay catalysis, and the reaction occurred via successive O-alkylation and C-H activation processes, both of which were promoted by the same catalyst.
Palladium-Nanoparticles-Catalyzed Oxidative Annulation of Benzamides with Alkynes for the Synthesis of Isoquinolones
Sharma, Nidhi,Saha, Rajib,Parveen, Naziya,Sekar, Govindasamy
supporting information, p. 1947 - 1958 (2017/06/09)
A novel method to synthesize isoquinolones via oxidative annulation of N-alkoxy benzamides and alkynes using binaphthyl-stabilized palladium nanoparticles (Pd-BNP) as catalyst has been developed. This methodology affords various isoquinolone derivatives in good to excellent yields with high regioselectivities in the presence of air as oxidant. N-Methoxybenzothioamide was also found to undergo oxidative annulation with alkyne successfully and provided a sulfur analogue of isoquinolones in moderate yields. The Pd-BNP catalyst was easily recovered and reused up to four times without any apparent agglomeration. (Figure presented.).
