1349700-49-7

Upstream product

• 1008-89-5 2-phenylpyridine 
• 529-20-4 2-methylphenyl aldehyde 
• 118-90-1 ortho-methylbenzoic acid 
• 3034-79-5 bis(2-methylbenzoyl) peroxide 
• 933-88-0 ortho-toluoyl chloride 
• 611-15-4 1-methyl-2-vinyl-benzene 
• 89-93-0 ortho-methylbenzylamine 
• 16814-26-9 bis(2-methylbenzyl) ether 
• 57139-25-0 N-methoxy-2-methylbenzamide 

Relevant academic research and scientific papers

'Ligand-free' palladium-catalyzed direct C-H bond oxidative acyloxylation of 2-arylpyridines with aromatic carboxylic acids

A palladium-catalyzed direct C-H bond oxidative acyloxylation of 2-arylpyridines with aromatic carboxylic acids is described. Several 2-arylpyridines derivatives and aromatic carboxylic acids participate in the reaction, providing a series of mono-acyloxy

Amides and Ethers as Chemoselective Surrogates for Copper(II)-Catalyzed ortho Benzoyloxylation of 2-Phenylpyridines

Chemoselective ortho benzoyloxylation of 2-phenylpyridine derivatives using amides and ethers as novel arylcarboxy sources using a Cu(II)/TBHP catalytic system has been reported. It is a simple protocol for ortho benzoyloxylation using amides and ethers as surrogates. A broad range of amides and ethers was found to be compatible under optimized reaction conditions to provide the corresponding products in good to excellent yield. The reaction proceeds through the cleavage of C-N, C-O, and C-H bonds and the formation of a new C-O bond via C-H functionalization.

Benzylic ethers as arylcarboxy surrogates in substrate directed ortho C-H functionalisation catalysed by copper

A copper catalysed ortho-benzoxylation of 2-arylpyridines has been accomplished using benzylic ethers as the alternative arylcarboxy sources (ArCOO-) via sp2 C-H bond activation. The use of the Pd/TBHP catalytic system is reported to install an

Benzylamine as an arylcarboxy surrogate: A copper catalysed o-benzoxylation of 2-phenylpyridines using benzyl amines

Different reactivities and selectivities of Cu and Pd catalysts have been demonstrated in the reactions of benzylamines with 2-phenylpyridines. Although Pd is reported to give o-arylation (ArCO-), Cu introduces an arylcarboxy group (ArCOO-) at the proxima

Copper catalyzed oxidative ortho-C-H benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines as benzoxylation sources

A simple and efficient protocol for the oxidative ortho benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines via C-H bond activation has been developed. The present protocol uses benzyl alcohol and benzyl amine as inexpensive and easi

Terminal aryl alkenes and alkynes as arylcarboxy surrogates toward o -Benzoxylation of 2-phenylpyridine catalyzed by copper

A variety of styrenes and phenylacetylenes serve as excellent arylcarboxy sources in bringing about substrate directed o-benzoxylation of 2-phenylpyridine derivatives catalyzed by Cu(II) in the presence of TBHP. This reaction proceeds via formation of phenylglyoxal followed by decarbonylation to benzoyl radical/benzaldehyde which acts as the arylcarboxy source.

Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.

Copper-catalyzed domino oxidation-acyloxylation reaction of 2-arylpyridines with aldehydes or methylarenes

A domino oxidation-acyloxylation reaction of 2-arylpyridines with aldehydes or methylarenes under the catalysis of Cu(OAc)has been developed. The strategy via C-H bond functionalization has the advantages of good functional-group tolerance, high ortho reg