57152-93-9Relevant academic research and scientific papers
Highly regioselective lipase-catalyzed acetylation and hydrolysis of acyclic α,ω-terpenediols and their diacetates
Takabe, Kunihiko,Mase, Nobuyuki,Hisano, Takaya,Yoda, Hidemi
, p. 3267 - 3269 (2007/10/03)
Highly regioselective transformations of the acyclic α,ω-terpenediols and their diacetates to the monoacetates using lipase were accomplished. The acetylation of the α,ω-terpenediols gave regioselectively the ω-monoacetates 3, whereas the α-monoacetates 2 were obtained by hydrolysis of the α,ω-diacetates.
Synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids
Ward, Jane L.,Beale, Michael H.
, p. 710 - 712 (2007/10/03)
The synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) was described by regioselective hydroxylation and diphosphorylation of dimethylallyl alcohol. The synthesis started from commercially available 3-methylbut-2-en-1-ol. The 1-alcohol function of starting material was converted to the acetate by treatment with pyridine acetic anhydride. Selective allylic hydroxylation was achieved using selenium dioxide and tert-butyl hydro-peroxide.
