57162-72-8Relevant academic research and scientific papers
Novel 2,4-diaryl-indenopyridine derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition containing the same for preventing or treating cancer as active ingredients
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Paragraph 0152; 0463-0465, (2016/11/17)
The present invention relates to a novel 2,4-diaryl-indenopyridine derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active component for preventing and treat
A novel and efficient 2,4,6-trisubstituted pyridine ring synthesis via α-benzotriazolyl ketones
Katritzky, Alan R.,Abdel-Fattah, Ashraf A. A.,Tymoshenko, Dmytro O.,Essawy, Samy A.
, p. 2114 - 2118 (2007/10/03)
Reaction of α-benzotriazolyl ketones with α,β-unsaturated ketones resulted in 2,4,6-triarylpyridines, 2,4-diaryl-5H-indeno[1,2-b]pyridines and 2,4-diaryl-5,6-dihydrobenzo[h]quinolines in good yields.
REACTIONS OF 1,5-DIKETONES LII. CYCLIZATION OF 2-METHYLENE-3-PHENYL 1,5-DIKETONES UNDER THE ACTION OF SULFURIC ACID
Pavel', K. G.,Pavel', G. V.,Vysotskii, V. I.,Tilichenko, M. N.
, p. 1405 - 1408 (2007/10/02)
In the action of sulfuric acid on 2-(2-benzoyl-1-phenylallyl)-3,4-dihydro-2(1H)-naphthalenone, 2,4-dibenzoyl-3-phenyl-1-alkenes, and 2,4-dibenzoyl-3-phenyl-1,4-pentadiene substituted 3-benzoyl-2,3-dihydro-4H-pyrans and also 1,5-diketones of the indan seri
On the Reaction of N-Vinyliminophosphoranes. Part 16. A New Synthesis of 5H-Indenopyridines and 5H-Indenopyridin-5-ones
Nitta, Makoto,Ohnuma, Manami,Iino, Yukio
, p. 1115 - 1118 (2007/10/02)
Thermal reaction of tributyl(inden-3-ylimino)phosphorane with α,β-unsaturated ketones and aldehydes led to a Michael-type C-C bond formation and subsequent aza-Wittig reaction to give 5H-indeno(1,2-b)pyridines in good to modest yield.The products were oxidized conveniently by chromium trioxide and t-butyl hydroperoxide to give 5H-indenopyridin-5-ones, including the 4-azafluorenone alkaloid onychine.
CATALYTIC DEHYDROCYCLIZATION OF 3-ISOPROPYL(n-PROPYL)-2,6-DIPHENYLPYRIDINE AND 3-n-PROPYL-2,4,6-TRIPHENYLPYRIDINE
Prostakov, N.S.,Varlamov, A.V.,Borisova, T.N.
, p. 519 - 521 (2007/10/02)
The catalytic dehydrocyclization of 3-isopropyl-2,6-diphenylpyridine proceeds in two directions: conversion to 10-methyl-3-phenyl-4-azaphenanthrene and conversion to 9,9-dimethyl-4-azafluorene.C(9)-Unsubstituted 4-azafluorenes were obtained in
Kinetics and Mechanisms of Nucleophilic Displacements with Heterocycles as Leaving Groups. 2. N-Benzylpyridinium Cations: Rate Variation with Steric Effects in the Leaving Group
Katritzky, Alan R.,El-Mowafy, Azzahra M.,Musumarra, Giuseppe,Sakizadeh, Kumars,Sana-Ullah, Choudhry,et al.
, p. 3823 - 3830 (2007/10/02)
N-Benzyl groups are transferred to piperidine from pyridinium ions by unimolecular SN1 and/or bimolecular SN2 mechanisms.Steric acceleration by α-phenyl groups is reduced by an adjacent β-methyl group but increased by constraining th
Boron Trifluoride as a Cyclodehydrating Agent: Synthesis of Nitrogen Heterocycles via Pyrylium Tetrafluoroborates
Elshafie, Sayed M. M.
, p. 427 - 428 (2007/10/02)
Pyrylium cations (1-12,Z = O+) have been prepared in high yields by the interaction of chalkones (in slight excess) and different ketones using BF3-etherate as cyclodehydrating agent or from 1,5-diketones in the presence of HBr and chalkone as hydrogen abstractor.The pyrylium cations have been converted into the corresponding nitrogen heterocycles (1-12;Z=N).
