5719-34-6

Basic information

• Product Name: 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol
• Synonyms: 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol;5,7-Dihydrothieno[3,4-d]pyrimidine-2,4(1H,3H)-dione
• CAS NO: 5719-34-6
• Molecular Formula: C₆H₆N₂O₂S
• Molecular Weight: 170
• Mol File: 5719-34-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 300 °C
• Appearance: /
• Density: 1.58±0.1 g/cm3(Predicted)
• PKA: 9.88±0.20(Predicted)
• CAS DataBase Reference: 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol(5719-34-6)
• EPA Substance Registry System: 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol(5719-34-6)

Safety Data

• Hazardous Substances Data: 5719-34-6(Hazardous Substances Data)

Usage

General Description

5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol is a chemical compound with the molecular formula C6H6N2O2S. It is a heterocyclic compound that contains a thieno[3,4-d]pyrimidine ring system and two hydroxyl groups. 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol has been studied for its potential pharmaceutical properties, including its use as an inhibitor of protein kinase C and as a potential anti-cancer agent. It has also been investigated for its potential in the treatment of diabetes and neurological disorders. The synthesis and properties of 5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol continue to be the subject of ongoing research in the fields of medicinal chemistry and drug development.

Upstream product

• 2689-68-1 methyl 4-oxotetrahydrothiophene-3-carboxylate 
• 78647-31-1 Methyl tetrahydro-4-oxo-3-thiophenecarboxylate 
• 7400-45-5 dimethyl-3-thiaadipate 
• 5719-20-0 5H,7H-2-ethylthiodihydrothieno<3,4-d>pyrimidin-4-one 

Downstream Products

• 74901-71-6 2,4-dichloro-5,7-dihydrothieno[3,4-d]pyrimidine 
• 1429638-92-5 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-93-6 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1054664-68-4 C₃₂H₂₆N₂O₉S 

Relevant articles and documents

MORPHOLINO SUBSTITUTED BICYCLIC PYRIMIDINE UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS

The invention relates to compounds of formula (I) wherein m, o, Ra, Rb, R1 and T1 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments

COMPOUNDS ACTIVE ON GLUTAMATERGIC RECEPTORS

The present invention relates to a compound of Formula (I) process for its preparation and uses thereof.

Synthesis of Cyclic and Acyclic Nucleoside Analogues Having a Thiophene or Dihydrothiophene Ring Fused to the d Side of an Uracil

Synthesis of cyclic and acyclic nucleosides was achieved by alkylation of various new aglycones following the Vorbrueggen and Niedballa's procedure .The analytical results allowed us to conclude that the alkylation ocurred on N1 site led to the β anomeric form for the cyclic nucleosides.