57193-97-2

Basic information

• Product Name: Benzonitrile, 4-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• CAS NO: 57193-97-2
• Molecular Formula: C16H13NO
• Molecular Weight: 235.285
• Mol File: 57193-97-2.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[2-(4-methoxyphenyl)ethenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[2-(4-methoxyphenyl)ethenyl]-, (E)-(57193-97-2)
• EPA Substance Registry System: Benzonitrile, 4-[2-(4-methoxyphenyl)ethenyl]-, (E)-(57193-97-2)

Safety Data

• Hazardous Substances Data: 57193-97-2(Hazardous Substances Data)

Upstream product

• 1552-41-6 diethyl [(4-cyanophenyl)methyl]phosphonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 26104-68-7 (p-cyanobenzyl)triphenylphosphonium bromide 
• 623-03-0 4-Cyanochlorobenzene 
• 637-69-4 4-Methoxystyrene 
• 28255-72-3 4-Cyanphenylphosphonsaeurediethylester 
• 696-62-8 para-iodoanisole 
• 183241-44-3 4-[(1E)-2-iodoethenyl]benzonitrile 
• 1133034-67-9 4-((Z)-2-iodovinyl)benzonitrile 
• 3319-15-1 rac-1-(4-methoxyphenyl)-ethanol 
• 623-00-7 4-bromobenzenecarbonitrile 
• 16642-94-7 (E)-4-cyanocinnamic acid 
• 67205-73-6 2-(4-bromophenyl)-1-(4-methoxyphenyl)-1-ethanone 
• 17201-43-3 4-cyanobenzyl bromide 

Downstream Products

• 67205-75-8 (E)-ethyl 4-(4-methoxystyryl)benzoate 
• 136827-57-1 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile 
• 66003-94-9 (Z)-4-(4-methoxystyryl)benzonitrile 
• 67206-05-7 4-[4-(4-methoxyphenethyl)benzyl]heptane-3,5-dione 

Relevant articles and documents

Efficient deep blue emission by 4-styrylbenzonitrile derivatives in solid state: Synthesis, aggregation induced emission characteristics and crystal structures

Organic fluorescent molecules with π-conjugated system have shown great importance in numerous applications including bioimaging and optoelectronics. Planar aggregation-induced emissive (AIE) organic compounds with efficient solid-state luminescence are rarely developed and urgently needed in various applications. In this work, highly planar 4-styrylbenzonitrile derivatives have been synthesized. Most of these compounds show strong AIE properties with hundred-fold fluorescent enhancement. Moreover, these molecules are deep blue emissive in solid state, exhibiting good to excellent fluorescence quantum efficiency. The single crystal analysis shows that adjacent molecules could form special J-type aggregation. The intramolecular rotations are efficiently restricted by various noncovalent interactions. These molecular arrangements could be essential for the observed strong emission in aggregated and solid state. This work has paved a new path to efficient AIE-active organic emitters with highly planar conformations from 4-styrylbenzonitrile structure.

Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation

Inhibition of lysine-specific demethylase 1 (LSD1) has recently emerged as an attractive therapeutic target for treating cancer and other diseases. As a continuity of our ongoing effort to identify novel small-molecule LSD1-inhibitors, we designed and syn

Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor

The invention discloses a resveratrol derivative, a synthesizing method thereof and application of the resveratrol derivative serving as a histone lysine specificity demethylase 1 inhibitor and belongs to the field of medicinal chemistry. The formula of the resveratrol derivative is as shown in the specification, wherein R is preferably hydrogen, hydroxyl, methoxy, nitro or halogen, and X represents N atom and C atom. The resveratrol derivative has good inhibitory effect on the histone lysine specificity demethylase 1 and can be used as the candidate for further development or the lead compound to develop medicine for treating diseases such as tumors and AIDS.