57222-08-9

Upstream product

• 13218-13-8 nitroacetonitrile 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 247079-72-7 2-amino-4-(4-methoxy-phenyl)-7-methyl-3-nitro-4H-pyrano[4,3-b]pyran-5-one 
• 39807-65-3 4-(4'-methoxyphenyl)-1H-1,2,3-triazole-5-carbonitrile 
• 928206-95-5 5-(4-methoxyphenyl)-1,2,3-(2H)-triazole-4-carbonitrile 
• 1421709-26-3 3-(4-dimethylaminophenyl)-3-(4-methoxyphenyl)-2-nitropropanenitrile 
• 75159-07-8 1-(4-methoxylphenyl)-2,3-diaza-4-(9-fluorenylidene)buta-1,3-diene 

Relevant academic research and scientific papers

New stable form of nitroacetonitrile

Oxidation of ethyl cyanoglyoxylate 2-oxime followed by KOH treatment affords stable potassium salt of nitroacetonitrile which is a reliable substitute of hazardous free nitroacetonitrile in organic synthesis.

Novel synthesis scheme and in vitro antimicrobial evaluation of a panel of (E)-2-aryl-1-cyano-1-nitroethenes

Drug resistance has become a major concern in the field of infection management, therefore searching for new antibacterial agents is getting more challenging. Our study presents an optimized and eco-friendly synthesis scheme for a panel of nitroalkenes be

Aryl(hetaryl)-containing gem-cyanonitroethenes: Synthesis, structure, and reactions with 2,3-dimethyl-1,3-butadiene

Methods of aryl(hetaryl)-substituted gem-cyanonitroethenes preparation are summarized, and the products structure elucidation by means of 1H, 13C NMR, IR, and UV spectroscopy methods is discussed. E-Configuration of the compounds obt

Silica-Gel-Catalysed Knoevenagel Condensation of Peptidyl Cyanomethyl Ketones with Aromatic Aldehydes and Ketones. A Novel Michael Acceptor Functionality for C-Modified Peptides: The Benzylidene and Alkylidene Cyanomethyl Ketone Function

Simple preparation of cyanomethyl ketone derivatives 5a-5b of N-acetylphenylalanine and N-acetylleucylphenylalanine is accomplished by condensation of the corresponding activated carboxylic acids 3a-3b and the carbanion of tert-butyl cyanoacetate to give