5724-06-1

Basic information

• Product Name: 4-Pentenoic acid,5-(4-methoxyphenyl)-
• Synonyms: 4-Pentenoicacid, 5-(p-methoxyphenyl)- (7CI,8CI)
• CAS NO: 5724-06-1
• Molecular Formula: C12H14 O3
• Molecular Weight: 206.241
• Mol File: 5724-06-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 4-Pentenoic acid,5-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid,5-(4-methoxyphenyl)-(5724-06-1)
• EPA Substance Registry System: 4-Pentenoic acid,5-(4-methoxyphenyl)-(5724-06-1)

Safety Data

• Hazardous Substances Data: 5724-06-1(Hazardous Substances Data)

Upstream product

• 25305-58-2 ethyl 5-(4-methoxyphenyl)-5-oxopentanoate 
• 591-80-0 pent-4-enoic acid 
• 696-62-8 para-iodoanisole 
• 637-69-4 4-Methoxystyrene 
• 124-38-9 carbon dioxide 
• 16510-27-3 1-(cyclopropylmethyl)-4-methoxybenzene 
• 60633-18-3 (3-carboxy-propyl)triphenylphosphonium chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 212777-65-6 dimethyl [(2E)-3-(4-methoxyphenyl)prop-2-en-1-yl]malonate 
• 90841-43-3 (E)-4-methoxycinnamyl bromide 
• 53484-50-7 (E)-p-methoxy-cinnamyl alcohol 
• 24393-56-4 ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate 
• 104-88-1 4-chlorobenzaldehyde 
• 61691-82-5 1'-acetoxyestragole 

Downstream Products

• 5724-01-6 Bis-<4-<4-methoxy-benzyliden>-butyryl>-peroxid 
• 24962-83-2 (±)-5-(4-methoxybenzyl)dihydrofuran-2(3H)-one 
• 24962-85-4 (+/-)-5-(4-methoxyphenylcarbonyl)dihydrofuran-2(3H)-one 
• 1415637-35-2 (5R,6S)-5-iodo-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-one 

Relevant articles and documents

Synthesis of Antitricyclic Morpholine Derivatives through Iodine(III)-Mediated Intramolecular Umpolung Cycloaddition of Olefins

A (diacetoxyiodo)benzene-mediated intramolecular cycloaddition of olefins to construct tricyclic morpholines is presented. A series of substituted tricyclic morpholines were obtained in one-step simple operation under mild conditions, and the NMR studies

HFIP Solvent Enables Alcohols to Act as Alkylating Agents in Stereoselective Heterocyclization

A new method for the stereoselective synthesis of highly functionalized oxygen heterocycles using allyl or benzyl alcohols as alkylating agents is presented. The process is efficient and atom economic, generating water as the only stoichiometric byproduct. Substoichiometric amounts of Ti(OiPr)4 in HFIP solvent are key to this reactivity, and the method tolerates a broad substitution pattern on both the alcohol initiator and homoallylic alcohol substrate. Preliminary mechanistic studies reveal in situ formation of a titanium complex with HFIP which may initiate the cyclization reaction. Further stereoselective functionalization of the products allows access to a diverse range of interesting heterocyclic structures.

Reversing the Regioselectivity of Halofunctionalization Reactions through Cooperative Photoredox and Copper Catalysis

Halofunctionalization of alkenes is a classical method for olefin difunctionalization. It gives rise to adducts which are found in many natural products and biologically active molecules, and offers a synthetic handle for further manipulation. Classically, this reaction is performed with an electrophilic halogen source and leads to regioselective formation of the halofunctionalized adducts. Herein, we demonstrate a reversal of the native regioselectivity for alkene halofunctionalization through the use of an acridinium photooxidant in conjunction with a copper cocatalyst.