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Benzenemethanol, 3-(acetyloxy)-, acetate, also known as 3-(acetyloxy)benzenemethanol acetate, is an organic compound with the chemical formula C11H12O4. It is a colorless liquid that is soluble in most organic solvents. Benzenemethanol, 3-(acetyloxy)-, acetate is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. It is synthesized through the esterification of 3-(acetyloxy)benzenemethanol with acetic acid, resulting in the formation of an ester linkage. Due to its reactivity and versatility, it plays a crucial role in the development of new chemical entities and the modification of existing ones.

57281-56-8

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57281-56-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 57281-56-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,8 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57281-56:
(7*5)+(6*7)+(5*2)+(4*8)+(3*1)+(2*5)+(1*6)=138
138 % 10 = 8
So 57281-56-8 is a valid CAS Registry Number.

57281-56-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name acetic acid,[3-(hydroxymethyl)phenyl] acetate

1.2 Other means of identification

Product number -
Other names 3-hydroxybenzyl alcohol acetic acid diester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57281-56-8 SDS

57281-56-8Relevant academic research and scientific papers

Selective acylation of the phenolic hydroxyl of (hydroxyalkyl)phenols by using vinyl carboxylates as acyl donors in the presence of rubidium fluoride

Miyazawa, Toshifumi,Yamamoto, Masato,Danjo, Hiroshi

, p. 1351 - 1354 (2013/10/01)

Highly selective acylation of the phenolic hydroxy group can be achieved with (hydroxyalkyl)phenols carrying both alcoholic and phenolic hydroxyls by the use of vinyl carboxylates as acyl donors in the presence of rubidium fluoride.

Liquid-phase reactions of isomeric methylphenols with ozone

Galstyan

scheme or table, p. 15 - 19 (2010/05/01)

Ozonation of isomeric methylphenols in acetic anhydride was studied. Here, acetic anhydride acts simultaneously as solvent and acylating agent. In the presence of a mineral acid methylphenols were converted into methylphenyl acetates during preparation of solutions for ozonation. The major products in the oxidation of isomeric methylphenyl acetates with ozone were aliphatic peroxides (80-90%); oxidation of the methyl group gave rise to the corresponding acetoxybenzyl acetates (7-14%) and acetoxybenzylidene diacetates (3-6%). A probable scheme for the liquid-phase oxidation of methylphenyl acetates with ozone in acetic anhydride was proposed.

Study of reaction of isomeric acetoxytoluenes with ozone in liquid phase in the presence of manganese bromide catalyst

Galstyan,Sedykh

scheme or table, p. 948 - 952 (2011/01/07)

The kinetics of the ozone reaction with isomeric acetoxytoluenes in acetic anhydride in the presence of sulfuric acid and mixed manganese bromide catalyst was studied. Under these conditions it is possible to stop the oxidation process at the stage of formation of hydroxybenzaldehydes in the form of the respective acetoxybenzylidendiacetates (63-70%). The reaction products contain also acetoxybenzyl acetate (16-18%) and a small amount of acetoxybenzyl bromide (2%). The mechanism of oxidation-reduction catalysis with manganese bromide complex explaining the experimental data was considered. Pleiades Publishing, Ltd., 2010.

Microwave-accelerated selective acylation of (hydroxyalkyl)phenols using acid chlorides

Miyazawa, Toshifumi,Yamamoto, Masato,Maeda, Yuki

experimental part, p. 1092 - 1099 (2009/09/06)

Highly selective acylation of the alcoholic hydroxy group can be achieved with (hydroxyalkyl)phenols carrying both alcoholic and phenolic hydroxyls by the use of the most common acylating agents, acid chlorides, under microwave irradiation. Copyright Tayl

Regio- and Chemo-selective Properties of Lipase from Candida cylindracea

Pedrocchi-Fantoni, Giuseppe,Servi, Stefano

, p. 1029 - 1034 (2007/10/02)

Lipase from Candida cylindracea allows discrimination between the two connectively non-equivalent hydroxy groups in primary diols or their esters via acylation-hydrolysis, with high regioselectivity.The same technique is used to distinguish between hydroxy groups of different nature in phenolic compounds.

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