142784-72-3

Basic information

• Product Name: Benzenemethanol, 3-hydroxy-, a-acetate
• Synonyms: Acetic acid 3-hydroxy-benzyl ester;(3-Oxy-benzyl)-acetat;3-hydroxyphenylmethyl acetate;3-Oxy-11-acetoxy-1-methyl-benzol;3-Acetoxymethyl-phenol
• CAS NO: 142784-72-3
• Molecular Formula: C9H10O3
• Molecular Weight: 166.177
• Mol File: 142784-72-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 295 - 302 °C
• Density: 1.181±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, 3-hydroxy-, a-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-hydroxy-, a-acetate(142784-72-3)
• EPA Substance Registry System: Benzenemethanol, 3-hydroxy-, a-acetate(142784-72-3)

Safety Data

• Hazardous Substances Data: 142784-72-3(Hazardous Substances Data)

Upstream product

• 620-24-6 3-Hydroxybenzyl alcohol 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 2466-76-4 N-Acetylimidazole 
• 1198597-50-0 C₁₈H₃₀O₃Si 
• 75-36-5 acetyl chloride 
• 1114567-54-2 3-(tert-butyldiphenylsilyloxy)benzyl acetate 
• 226070-43-5 3-(tert-butyldimethylsilyloxy)benzyl acetate 
• 141-78-6 ethyl acetate 
• 57281-56-8 m-Acetoxybenzyl acetate 
• 108-05-4 vinyl acetate 

Relevant articles and documents

Practical Chemoselective Acylation: Organocatalytic Chemodivergent Esterification and Amidation of Amino Alcohols with N-Carbonylimidazoles

Chemoselective transformations are a cornerstone of efficient organic synthesis; however, achieving this goal for even simple transformations, such as acylation reactions, is often a challenge. We report that N-carbonylimidazoles enable catalytic chemodivergent aniline or alcohol acylation in the presence of pyridinium ions or 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), respectively. Both acylation reactions display high and broad chemoselectivity for the target group. Unprecedented levels of chemoselectivity were observed in the DBU-catalyzed esterification: A single esterification product was obtained from a molecule containing primary aniline, alcohol, phenol, secondary amide, and N?H indole groups. These acylation reactions are highly practical as they involve only readily available, inexpensive, and relatively safe reagents; can be performed on a multigram scale; and can be used on carboxylic acids directly by in situ formation of the acylimidazole electrophile.

Lipase-mediated selective acetylation of primary alcohols in ethyl acetate

An environmental friendly process to selectively acetylate primary alcohols was demonstrated. The esterification process consists of treatment of a primary alcohol in the presence of immobilized C. antarctica lipase (Novozyme-435) in ethyl acetate at room temperature. Primary alcohols were acetylated in the presence of secondary alcohols and phenols.

A novel silver nanoparticle embedded mesoporous polyaniline (mPANI/Ag) nanocomposite as a recyclable catalyst in the acylation of amines and alcohols under solvent free conditions

A mesoporous polyaniline/silver (mPANI/Ag) nanocomposite has been prepared using mesoporous organic polymer polyaniline with silver nitrate via radical polymerization of aniline monomer in the presence of hydrochloric acid. The mPANI/Ag nanocomposite has been characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray spectra (EDX), Fourier transform infrared spectroscopy (FT-IR), and ultraviolet-visible absorption spectra (UV-vis). The XRD patterns indicated that the crystalline phase of Ag is cubic. TEM images show that the Ag nanoparticles are well dispersed in the mesoporous polyaniline matrix. The mPANI/Ag acts as an efficient heterogeneous nanocatalyst in the acylation of substituted amines and alcohols using acetic acid. The catalyst is air-stable, inexpensive, easy to prepare and can be reused several times without a significant decrease in activity and selectivity. This journal is