5730-75-6

Usage

Uses

Used in Organic Synthesis:
Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is utilized as a precursor in organic synthesis for a variety of reactions. Its versatility in chemical transformations makes it a key intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate serves as a crucial building block for the development of new drugs. Its unique structure and reactivity contribute to the creation of novel pharmaceutical compounds with potential therapeutic applications.
Used in Production of Pharmaceuticals:
Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is employed in the manufacturing process of certain pharmaceuticals. Its role as a precursor allows for the production of a range of medicinal compounds that address various health conditions.
Used in Agrochemicals Production:
Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate also finds application in the agrochemical sector, where it is used in the synthesis of various agrochemicals. Its contribution to the development of effective crop protection agents and other agricultural products is significant.
Used in Development of Novel Materials and Drugs:
Due to its distinctive structural attributes and chemical properties, Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is explored for its potential in the innovation of new materials and drug candidates, expanding the horizons of material science and medicinal chemistry.
Used as a Reference Standard in Analytical Chemistry:
Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is also used as a reference standard in analytical chemistry. It aids in the calibration of instruments and the validation of analytical methods, ensuring the accuracy and reliability of chemical measurements.
Used in Quality Control Processes:
In the quality control segment, Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is employed to ensure the consistency and purity of products in various industries. It serves as a benchmark for assessing the quality of synthesized compounds and final products.

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 586-78-7 para-nitrophenyl bromide 
• 67-56-1 methanol 

Downstream Products

• 92-89-7 4'-nitro-biphenyl-4-carboxylic acid 
• 5730-76-7 methyl 4’-amino-[1,1’-biphenyl]-4-carboxylate 
• 2143-88-6 4-nitro-4'-methyl-1,1'-biphenyl 
• 1204-78-0 4-(4-methylphenyl)aniline 
• 137058-70-9 4'-amino-1,1'-biphenyl-4-carboxylic acid benzyl ester 
• 1332882-94-6 4'-({(R)-2,3-bis[di(tert-butoxycarbonylmethyl)amino]propionyl}amino)-1,1'-biphenyl-4-carboxylic acid benzyl ester 
• 5730-78-9 4-(4-aminophenyl)benzoic acid 

Relevant academic research and scientific papers

The suzuki-miyaura reaction performed using a palladium-n-heterocyclic carbene catalyst and a weak inorganic base

N-Heterocyclic carbenes (NHCs) have been shown to be useful ligands for the Suzuki-Miyaura cross-coupling at low catalyst loadings. We now report that the commercially available and air-stable [Pd(IPr)(cin)Cl] pre-catalyst permits the formation of various functionalized biaryls from aryl chlorides and boronic acids (37 examples) under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base. [Pd(IPr)(cin)Cl] permits an operationally simple Suzuki-Miyaura reaction under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base.

Monodispersed and stable nano copper(0) from copper- aluminium hydrotalcite: Importance in C-C couplings of deactivated aryl chlorides

A simple one-step approach for the preparation of highly monodispersed nano copper(0) stabilized on alumina [Cu(0)/Al2O3] by thermal reduction of copper-aluminium hydrotalcite (Cu-Al HT) under a hydrogen atmosphere is described. The transformation of Cu-Al HT to Cu(0)/Al 2O3 occurrs via dehydroxylation of divalent and trivalent metal hydroxides and decarboxylation of carbonate anions present in the interlayers of hydrotalcite, as confirmed by XPS, XANES, XRD and TEM analysis. Cu(0)/Al2O3 nano composites were used as an efficient catalyst in the C-C coupling of deactivated aryl chlorides. The high efficiency and reusability exhibited by Cu(0)/Al2O3 outline its potential as an alternative over traditional noble metal-based catalysts in C-C coupling reactions. Copyright

Dynamics of the glycosidic bond: Conformational space of lactose

The dynamics of the glycosidic bond of lactose was studied by a paramagnetic tagging-based NMR technique, which allowed the collection of an unusually large series of NMR data for a single compound. By the use of distance- and orientation-dependent residual dipolar couplings and pseudocontact shifts, the simultaneous fitting of the probabilities of computed conformations and the orientation of the magnetic susceptibility tensor of a series of lanthanide complexes of lactose show that its glycosidic bond samples syn/syn, anti/syn and syn/anti φ/I regions of the conformational space in water. The analysis indicates a higher reliability of pseudocontact shift data as compared to residual dipolar couplings with the presently available weakly orienting paramagnetic tagging technique. The method presented herein allows for an improved understanding of the dynamic behaviour of oligosaccharides. Copyright

Photoactivatable HNO-releasing compounds using the retro-Diels-Alder reaction

We synthesized hetero-Diels-Alder cycloadducts from acyl nitroso derivatives and 9,10-dimethylanthracene, to be photo-inducible HNO-releasing agents and found that introduction of conjugated nitroaromatic groups effectively enhanced the responsiveness of HNO release to UV-A irradiation; we confirmed photoinduced HNO formation by EPR and GCMS analysis. The Royal Society of Chemistry.

Heterobifunctional pan-selectin inhibitors

Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).

Use of functionalized onium salts as a soluble support for organic synthesis

The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A1+, X1?, wherein A1+ represents a cation and X1? represents an anion.

HETEROBIFUNCTIONAL COMPOUNDS FOR SELECTIN INHIBITION

Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise glycomimetics linked to a compound, for example a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).

SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS

Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a particular glycomimetic linked to a particular BASA (Benzyl Amino Sulfonic Acid).