5739-98-0

Basic information

• Product Name: 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE
• Synonyms: 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE;6,7-Dimethoxy-2-hydroxyquinoxaline;6,7-DiMethoxy-2(1H)-quinoxalinone;6,7-diMethoxyquinoxalin-2-ol;6,7-Dimethoxyquinoxalin-2(1H)-one;6,7-diMethoxy-1H-quinoxalin-2-one
• CAS NO: 5739-98-0
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.2
• Mol File: 5739-98-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 295-296℃
• Boiling Point: 408.7 °C at 760 mmHg
• Flash Point: 201 °C
• Appearance: /
• Density: 1.33
• Vapor Pressure: 2.89E-07mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE(5739-98-0)
• EPA Substance Registry System: 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE(5739-98-0)

Safety Data

• Hazardous Substances Data: 5739-98-0(Hazardous Substances Data)

Usage

General Description

2-Hydroxy-6,7-dimethoxyquinoxaline is a chemical compound belonging to the class of organic compounds known as quinoxalines. It has a role as a metabolite and contains two methoxy groups attached to the 6 and 7 positions of its quinoxaline nucleus, along with a hydroxy group attached to the 2 position. The methoxy groups contribute to its lipophilicity, while the hydroxy group increases its water solubility. Its molecular formula is C10H10N2O3. 2-HYDROXY-6,7-DIMETHOXYQUINOXALINE has potential use in the development of pharmaceuticals and as a research tool in biochemistry and pharmacology.

InChI:InChI=1/C10H10N2O3/c1-14-8-3-6-7(4-9(8)15-2)12-10(13)5-11-6/h3-5H,1-2H3,(H,12,13)

Upstream product

• 3395-03-7 4,5-dimethoxy-1,2-dinitrobenzene 
• 924-44-7 glyoxylic acid ethyl ester 
• 27841-33-4 4,5-dimethoxybenzene-1,2-diamine 

Downstream Products

• 216699-86-4 2-chloro-6,7-dimethoxyquinoxaline 
• 221064-59-1 N-(2-Chloro-6-methylphenyl)-7,8-dihydroxyimidazo[1,5-a]quinoxalin-4-amine 
• 221063-10-1 N-(2-Chloro-6-methylphenyl)-7,8-dimethoxyimidazo[1,5-a]quinoxalin-4-amine 
• 357637-52-6 7,8-dimethoxy-5-(4-methoxy-benzyl)-5H-imidazo[1,5-a]quinoxalin-4-one 
• 357637-43-5 6,7-dimethoxy-1-(4-methoxy-benzyl)-1H-quinoxalin-2-one 

Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS

The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans.

Synthesis and SAR of novel imidazoquinoxaline-based Lck inhibitors: Improvement of cell potency

A series of anilino(imidazoquinoxaline) analogues bearing solubilizing side chains at the 6- and 7-positions of the fused phenyl ring has been prepared and evaluated for inhibition against Lck enzyme and of T-cell proliferation. Significant improvement of the cellular activity was achieved over the initial lead, compound 2.