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Cas No: 5746-86-1
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality 3-(2-Pyrrolidinyl)Pyridine supplier in China
Cas No: 5746-86-1
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Cas No: 5746-86-1
No Data 1 Kilogram 1 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
Factory Supply 3-(2-Pyrrolidinyl)Pyridine
Cas No: 5746-86-1
No Data 1 1 Ality Chemical Corporation Contact Supplier
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Cas No: 5746-86-1
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier
Factory Supply High Quality CAS 5746-86-1 ,3-(2-Pyrrolidinyl)pyridine CAS NO.5746-86-1
Cas No: 5746-86-1
No Data 10 Kilogram 100 Metric Ton/Month Wuhan Han Sheng New Material Technology Co.,Ltd Contact Supplier
BLOOM TECH Advanced API/Technology support 3-(Pyrrolidin-2-yl)pyridine CAS 5746-86-1
Cas No: 5746-86-1
No Data 1 Gram 3 Metric Ton/Month Shaanxi BLOOM TECH Co.,Ltd Contact Supplier
Pyridine,3-(2-pyrrolidinyl)- 5746-86-1
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No Data 1 Kilogram 10000 Metric Ton/Month Shanghai Upbio Tech Co.,Ltd Contact Supplier
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No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Pyridine,3-(2-pyrrolidinyl)-/ LIDE PHARMA- Factory supply / Best price
Cas No: 5746-86-1
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5746-86-1 Usage


(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC50 values of approximately 4 and 17 μM, respectively, when expressed in Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.

Chemical Properties

Colourless Oil


Different sources of media describe the Uses of 5746-86-1 differently. You can refer to the following data:
1. A metabolite of Nicotine ((N412420). Can catalyze aqueous aldol reactions.
2. 3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).
3. A metabolite of Nicotine. Can catalyze aqueous aldol reactions

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 1137, 1996 DOI: 10.1016/0040-4039(96)00002-0

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE

Check Digit Verification of cas no

The CAS Registry Mumber 5746-86-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,4 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5746-86:
121 % 10 = 1
So 5746-86-1 is a valid CAS Registry Number.

5746-86-1 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Alfa Aesar (L10809)  DL-Nornicotine, 98%    5746-86-1 10mg 489.0CNY Detail
Alfa Aesar (L10809)  DL-Nornicotine, 98%    5746-86-1 50mg 1696.0CNY Detail
USP (1463371)  Nicotine Related Compound F  United States Pharmacopeia (USP) Reference Standard 5746-86-1 1463371-20MG 14,500.98CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name 3-(2-Pyrrolidinyl)pyridine

1.2 Other means of identification

Product number -
Other names 3-pyrrolidin-2-yl-pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5746-86-1 SDS

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