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Brovincamine is a chemical compound that serves as a valuable reagent in the synthesis of various pharmaceutical products, particularly Vincamine (V314030(P)). It plays a significant role in the development of medications for the treatment of cerebral insufficiencies and related conditions.

57475-17-9

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57475-17-9 Usage

Uses

Used in Pharmaceutical Industry:
Brovincamine is used as a reagent for the synthesis of Vincamine (V314030(P)) for the treatment of cerebral insufficiencies. Its role in the production of this medication is crucial, as Vincamine is known to improve blood flow to the brain, enhance cognitive function, and alleviate symptoms associated with cerebral insufficiencies.

Check Digit Verification of cas no

The CAS Registry Mumber 57475-17-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,7 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57475-17:
(7*5)+(6*7)+(5*4)+(4*7)+(3*5)+(2*1)+(1*7)=149
149 % 10 = 9
So 57475-17-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H25BrN2O3/c1-3-20-8-4-9-23-10-7-15-14-6-5-13(22)11-16(14)24(17(15)18(20)23)21(26,12-20)19(25)27-2/h5-6,11,18,26H,3-4,7-10,12H2,1-2H3/t18-,20+,21+/m1/s1

57475-17-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Brovincamine

1.2 Other means of identification

Product number -
Other names cis-11-bromovincamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57475-17-9 SDS

57475-17-9Downstream Products

57475-17-9Relevant academic research and scientific papers

SYNTHESIS OF VINCA ALKALOIDS AND RELATED COMPOUNDS, XLIX. AROMATIC SUBSTITUENT EFFECTS IN THE C-14 EPIMERIZATION

Moldvai, Istvan,Vedres, Andras,Szantay, Csaba,Toth, Gabor,Szantay, Csaba

, p. 109 - 118 (2007/10/02)

Some A-ring substituted vincamine derivatives and their C-14 epimers have been prepared and the aromatic substituent effects on the epimeric equilibrium of these compounds investigated.

HALOGENATION OF INDOLE ALKALOIDS WITH HALODIMETHYLSULFONIUM HALOGENIDS AND HALODIMETHYLSULFOXONIUM HALOGENIDS

Megyeri, Gabor,Keve, Tibor

, p. 3415 - 3430 (2007/10/02)

A new field of application of halodimethylsulfonium halogenids and halodimethylsulfoxonium halogenids had been studied.The formers were used for the halogenation of indole alkaloids, compounds of ergoline or aspidospermidine structure, and vincamine.

Synthesis of Vinca Alkaloids and Related Compounds, XXXIV: Synthesis of (3S,14S,16S)-Bromovincamines and Bromoapovincamines by Regioselective Bromination

Szabo, Lajos,Dobay, Laszlo,Kalaus, Gyoergy,Gacs-Baitz, Eszter,Tamas, Jozsef,Szantay, Csaba

, p. 781 - 789 (2007/10/02)

By bromimation of the iminium salt 2a (X=Cl), the 9-bromo derivative 2c (X=ClO4) is obtained in isomer-free state.Bromination of the lactam 8d leads to ca. 7.5:1 mixture of 11-bromo (8c) and 9-bromo (8a) lactams.These precursors have been used to synthesize 9-, 10- and 11-bromovincamines (11a-c), and 9-, 10- and 11-bromoapovincamines (12a-c).

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