57492-91-8

Upstream product

• 57492-90-7 1-O-benzoyl-2,3-O-isopropylidene-α-D-mannofuranoside 
• 7306-64-1 2,3,5,6-di-O-isopropylidene-D-mannono-1,4-lactone 
• 98-88-4 benzoyl chloride 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 36574-21-7 α-D-mannose 
• 57526-34-8 (+)-2,3:5,6-di-O-isopropylidene-α-D-mannofuranos-3-yl benzoate 

Downstream Products

• 57492-92-9 methyl 1-O-benzoyl-5,6,7,8-tetradeoxy-2,3-O-isopropylidene-D-lyxo-non-5,7-dienofuranuronate 
• 160765-89-9 (5Z)-1-O-benzoyl-5,6,7-trideoxy-2,3:8,9-di-O-isopropylidene-α-D-manno-non-5-enofuranoside 
• 122204-09-5 Benzoic acid (3aS,4R,6R,6aS)-6-[(E)-2-(diethoxy-phosphoryl)-vinyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl ester 
• 122204-14-2 Benzoic acid (3aS,4R,6R,6aS)-6-[(E)-2-(diethoxy-phosphoryl)-2-fluoro-vinyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl ester 
• 110808-28-1 1-O-benzoyl-2,3-O-isopropylidene-α-D-lyxofuranose 
• 122204-10-8 Benzoic acid (3aS,4R,6R,6aS)-6-[2-(diethoxy-phosphoryl)-ethyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl ester 
• 57492-93-0 methyl 1-O-benzoyl-5,6,7,8-tetradeoxy-2,3-O-isopropylidene-D-lyxo-nonofuranuronate 
• 129034-01-1 5-deoxy-2,3-O-isopropylidene-5-phenylthio-D-lyxitol 
• 129034-00-0 5-deoxy-2,3-O-isopropylidene-5-phenylthio-α-D-lyxofuranose 
• 129034-02-2 1-O-tert-butyldimethylsilyl-5-deoxy-2,3-O-isopropylidene-5-phenylthio-D-lyxitol 
• 129034-03-3 5-O-tert-butyldimethylsilyl-1-deoxy-3,4-O-isopropylidene-1-phenylthio-D-erythro-pentulose 
• 6730-43-4 Methyl-5-acetylamino-3,5-didesoxy-D-glycero-β-D-galakto-nonulopyranosidonsaeure-methylester 
• 129034-05-5 6-O-tert-butyldimethylsilyl-2-deoxy-4,5-O-isopropylidene-2-phenylthio-D-erythro-hex-1-eno-3-ulose 
• 129033-99-4 benzoyl 2,3-O-isopropylidene-5-O-methylsulfonyl-α-D-lyxofuranoside 

Relevant academic research and scientific papers

Synthesis of Chiral Polyhydroxylated Benzimidazoles by a Tandem Radical Fragmentation/Cyclization Reaction: A Straight Avenue to Fused Aromatic-Carbohydrate Hybrids

The synthesis of benzimidazole-fused iminosugars through a tandem β-fragmentation-intramolecular cyclization reaction is described. The use of the benzimidazole ring as the internal nucleophile and the use of phenyliodosophthalate (PhI(Phth)), a new metal-free and low toxic hypervalent iodine reagent, are the most remarkable novelties of this synthetic strategy. With this approach, we have demonstrated the usefulness of the fragmentation of anomeric alkoxyl radicals promoted by the PhI(Phth)/I2 system for the preparation of new compounds with potential interest for both medicinal and synthetic chemists.

An efficient and green oxidation of vicinal diols to aldehydes using polymer-supported (diacetoxyiodo)benzene as the oxidant

An operationally simple and clean oxidation of a variety of vicinal diols to aldehydes using polymer-supported (diacetoxyiodo)benzene (PSDIB) has been developed in high to excellent yields. Protecting groups such as OAc, OR, OBn, OBz and isopropylidene in the substrates were found to be stable under these reaction conditions. The regenerated PSDIB could be reused for the same reaction, affording oxidation products in high yield and purity. Georg Thieme Verlag Stuttgart.

Intramolecular nitrile oxide-alkene cycloaddition of sugar derivatives with unmasked hydroxyl group(s)

(Chemical Equation Presented) Intramolecular nitrile oxide-alkene cycloaddition (INOC) of sugar derivatives with one to four free hydroxyl group(s) is reported. The INOC reaction, using chloramine-T, in the presence of silica gel, to generate nitrile oxid

Synthesis of novel 1α,25-dihydroxy-19-norvitamin D3 with an amide conjugate

The diene system of 1α,25-dihydroxy-19-norvitamin D3 was replaced by a stable amide bond. A 3-hydroxypropoxy group, which was effective on enhancing binding affinity of 1α,25-dihydroxyvitamin D3 for vitamin D receptor (VDR), was introduced to the C2-position of the amide type analogue of 1α,25-dihydroxy-19-norvitamin D3. The amide analogue was found to be not suitable for binding to the ligand binding domain of the bovine thymus VDR, and additional modification at the C2-position did not improve the affinity. Potency in induction of HL-60 cell differentiation was evaluated for the novel amide analogues (3a-c).