577-62-8

Basic information

• Product Name: ETHYL 2-(TRIFLUOROMETHYL)BENZOATE
• Synonyms: ETHYL 2-(TRIFLUOROMETHYL)BENZOATE;2-(TRIFLUOROMETHYL)BENZOIC ACID ETHYL ESTER;RARECHEM AL BI 0046;Ethyl 2-(trifluoromethyl)benzoate 97%;Ethyl2-(trifluoromethyl)benzoate97%;Ethyl 2-(trifluoromethyl)benzoate, 98+%
• CAS NO: 577-62-8
• Molecular Formula: C₁₀H₉F₃O₂
• Molecular Weight: 218.17
• Mol File: 577-62-8.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 90 °C
• Flash Point: 90-91°C/10mm
• Appearance: /
• Density: 1.459
• Vapor Pressure: 0.0434mmHg at 25°C
• Refractive Index: 1.45
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 3290053
• CAS DataBase Reference: ETHYL 2-(TRIFLUOROMETHYL)BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(TRIFLUOROMETHYL)BENZOATE(577-62-8)
• EPA Substance Registry System: ETHYL 2-(TRIFLUOROMETHYL)BENZOATE(577-62-8)

Safety Data

• Hazard Codes: F
• Safety Statements: S24/25:Avoid contact with skin and eyes.
• PackingGroup: III
• Hazardous Substances Data: 577-62-8(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(trifluoromethyl)benzoate is a chemical compound that is commonly used as a flavoring and fragrance agent in the production of various consumer goods such as perfumes, cosmetics, and food products. It is also utilized in the synthesis of pharmaceuticals and agrochemicals. ETHYL 2-(TRIFLUOROMETHYL)BENZOATE is known for its fruity and sweet odor and is often used to impart a pleasant aroma to products. It is a clear, colorless liquid with a molecular formula of C10H9F3O2 and a molecular weight of 226.17 g/mol. The chemical is considered to be relatively stable and non-reactive under normal conditions, making it a commonly used additive in the production of fragrances and flavors.

InChI:InChI=1/C10H9F3O2/c1-2-15-9(14)7-5-3-4-6-8(7)10(11,12)13/h3-6H,2H2,1H3

Upstream product

• 75-46-7 trifluoromethan 
• 1829-28-3 ethyl 2-iodobenzoate 
• 93-89-0 benzoic acid ethyl ester 
• 82113-65-3 bis(trifluoromethanesulfonyl)amide 
• 444-30-4 2-(trifluoromethyl)phenol 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 105-58-8 Diethyl carbonate 
• 2926-29-6 Langlois reagent 
• 87-25-2 2-ethoxycarbonylaniline 
• 433-97-6 2-trifluoromethylbenzoic acid 
• 76-05-1 trifluoroacetic acid 
• 100-47-0 benzonitrile 

Relevant articles and documents

Pleuromutilin derivative with 1, 3, 4-oxadiazole side chain and preparation and application thereof

The invention belongs to the field of medicinal chemistry, and particularly relates to a pleuromutilin derivative with a 1, 3, 4-oxadiazole side chain and preparation and application thereof The pleuromutilin derivative with the 1, 3, 4-oxadiazole side chain is a compound shown in a formula 2 or a pharmaceutically acceptable salt thereof, and a solvent compound, an enantiomer, a diastereoisomer and a tautomer of the compound shown in the formula 2 or the pharmaceutically acceptable salt thereof or a mixture of the solvent compound, the enantiomer, the diastereoisomer and the tautomer in any proportion, including a racemic mixture. The pleuromutilin derivative has good antibacterial activity, is especially suitable for being used as a novel antibacterial agent for systemic system infection of animals or human beings, and has good water solubility.

Synthesis and bioactivity of sulfide derivatives containing 1,3,4-oxadiazole and pyridine

A series of novel sulfide derivatives containing 1,3,4-oxadiazole and pyridine were synthesized, characterized, and tested for their antibacterial activity against tobacco bacterial wilt and rice bacterial blight and for insecticidal activity toward diamondback moth. The results showed that some compounds had good insecticidal and bactericidal activity, e.g., the activities of compounds 6e and 6g–6j toward tobacco bacterial wilt were much better than those of commercial thiodiazole-copper, and some of the synthesized compounds possessed good insecticidal activity against Plutella xylostella. Compounds 6d, 6h, 6j, 6l, 6p, 6r, and 6p displayed over 93% activity at 500 mg L? 1.

SO2F2-Mediated One-Pot Synthesis of Aryl Carboxylic Acids and Esters from Phenols through a Pd-Catalyzed Insertion of Carbon Monoxide

A one-pot Pd-catalyzed carbonylation of phenols into their corresponding aryl carboxylic acids and esters through the insertion of carbon monoxide has been developed. This procedure offers a direct synthesis of aryl carboxylic acids and esters from inexpensive and abundant starting materials (phenols, SO2F2 and CO) under mild conditions. This method tolerates a broad range of functional groups and is also applicable for the modification of complicated natural products.