57722-04-0

Basic information

• Product Name: 1-chloro-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethane
• Synonyms: 1-chloro-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethane
• CAS NO: 57722-04-0
• Molecular Weight: 226.7
• Mol File: 57722-04-0.mol

Chemical Properties

• Boiling Point: 280.7±25.0 °C(Predicted)
• Density: 1.059±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-chloro-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethane(57722-04-0)
• EPA Substance Registry System: 1-chloro-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethane(57722-04-0)

Safety Data

• Hazardous Substances Data: 57722-04-0(Hazardous Substances Data)

Usage

Chemical class

Chloroalkyl ether

Physical state

Colorless liquid

Odor

Faint

Flammability

Highly flammable

Corrosiveness

Corrosive

Family

Glycol diether

Industrial applications

Solvent in various industries

Usage in production

Lithium batteries, pharmaceutical, and chemical industries

Environmental impact

Toxic to aquatic organisms, potential long-term adverse effects

Handling precautions

Handle with care, proper disposal to minimize environmental impact

Upstream product

• 75-21-8 oxirane 
• 67-56-1 methanol 
• 23783-42-8 tetraethylene glycol monomethyl ether 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 52808-36-3 1-chloro-2-(2-methoxyethoxy)ethane 

Downstream Products

• 57722-03-9 o-hydroxyphenyl 3,6,9,12-tetraoxatridecyl ether 
• 57721-96-7 1,2-Bis-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzene 
• 720681-03-8 3,5-bis-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester 
• 484046-55-1 methyl 3,4,5-tris(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)benzoate 
• 857934-58-8 3-methoxy-4-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)benzoic acid methyl ester 
• 928122-90-1 3-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)benzaldehyde 
• 484046-57-3 3,4,5-tris(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)benzyl alcohol 
• 168427-91-6 1-[(2R,3R,4R,5R)-4-(2,4-Dichloro-benzyloxy)-5-(2,4-dichloro-benzyloxymethyl)-3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 847342-67-0 2,2,2-trichloroacetimidic acid 3-methoxy-4-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)benzyl ester 
• 847342-63-6 [3-methoxy-4-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol 

Relevant articles and documents

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The principles of the oligoethylene glycol (OEG) mixture synthesis are illustrated with the synthesis of all four possible stereoisomers of a hydroxybutenolide fragment common to murisolin and many other acetogenins. Modified dimethoxybenzyl groups with varying numbers of OEG units (-CH 2CH2O-) are used to protect alcohols and serve as codes for configurations at two stereocenters. The encoded isomers are carried through several steps in a sequence of mixing prior to the reaction and then demixing during the separation to give individual pure products. A new tagging scheme is introduced in which a stereocenter bearing a hydroxy group is given two different tags. These initially redundant tags then serve to encode the configuration of another (untagged) stereocenter by appropriate pairwise reactions of the tagged precursors. The experimental features (reaction, analysis, separation, and characterization) of OEG mixture synthesis are detailed and are compared to and contrasted with those of fluorous mixture synthesis.

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