57770-87-3

Upstream product

• 6275-32-7 (2E,6E)-2,6-bis(4-methoxybenzylidene)cyclohexanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 108-94-1 cyclohexanone 
• 62085-71-6 2,6-bis(4-methoxybenzylidene)cyclohexanone 

Downstream Products

• 30386-04-0 2-acetyl-7-(4-methoxy-benzylidene)-3-(4-methoxy-phenyl)-3,3a,4,5,6,7-hexahydro-2H-indazole 
• 83391-30-4 (3R,3aS)-3-(4-Methoxy-phenyl)-7-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-3,3a,4,5,6,7-hexahydro-indazole-2-carbodithioic acid 
• 83391-07-5 {(3R,3aS)-3-(4-Methoxy-phenyl)-7-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-3,3a,4,5,6,7-hexahydro-indazol-2-yl}-methanol 
• 83391-17-7 (3R,3aS)-3-(4-Methoxy-phenyl)-7-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-2-nitroso-3,3a,4,5,6,7-hexahydro-2H-indazole 

Relevant academic research and scientific papers

Synthesis of 3,7-disubstituted hexahydro- and tetrahydro-2H-indazoles from cross-conjugated dienones

The oxidation of 3,7-disubstituted hexahydroindazoles with potassium hexacyanoferrate(III) afforded previously unknown tetrahydro-2H-indazole derivatives. A novel ring contraction reaction leading to 2,3-diazaspiro[4.4]non-3-en-1-one derivatives was discovered. The product structure was proved by NMR spectroscopy, mass spectrometry, and X-ray analysis.

Ene reactions of arylmethylenedihydropyrazoles with 4-phenyl-3H-1,2,4-triazole-3,5(4H)-dione

2-Acetyl-3-aryl-7-arylmethylene-3,4,5,6,7,9-hexahydro-2H-indazoles enter into the ene reaction with 4-phenyl-3H-1,2,4-triazole-3,5(4H)-dione to give the corresponding monoene adducts. Under analogous conditions, 3-aryl-7-arymethylene-2-methyl-3,4,5,6,7,9-hexahydro-2H-indazoles give mono- and polyaddition products. The structures of compounds obtained were established using UV, IR, 1H and 13C NMR spectroscopy and X-ray diffraction analysis.

Synthesis of Some New Bicyclic Pyrazoline Derivatives

2,6-Diarylidenecyclohexanones react with hydrazine to give the corresponding bicyclic pyrazolines.The synthesis of a series of twenty eight substituted pyrazolines is described.The structure of all products was confirmed by microanalyses, ir and nmr data.