5778-02-9

Upstream product

• 5778-16-5 3-phenyl-1-p-tolyl-isobenzofuran 
• 861299-54-9 2-methyl-9-phenyl-9,10-dihydro-9,10-episulfido-anthracene 
• 64-19-7 acetic acid 
• 85-52-9 2-Benzoylbenzoic acid 
• 108-88-3 toluene 
• 108-86-1 bromobenzene 
• 21615-75-8 3-(4-tolyl)-isobenzofuranone 
• 71-43-2 benzene 
• 22115-41-9 2-(bromomethyl)benzonitrile 
• 56153-61-8 2-benzyl-benzonitrile 
• 500311-02-4 2-benzyl-4'-methyl-benzophenone 

Downstream Products

• 5778-09-6 1-phenyl-4-p-tolylphthalazine 
• 1401613-66-8 C₃₁H₃₆O₄ 
• 23674-14-8 9-(4-methylphenyl)anthracene 

Relevant academic research and scientific papers

Synthesis of aromatic cycloketones via intramolecular Friedel-Crafts acylation catalyzed by heteropoly acids

Under liquid-phase conditions, the intramolecular Friedel?Crafts acylation of aryl benzoic acids catalyzed by heteropoly acids were investigated for the first time. Several aryl benzoic acids were refluxed and dehydrated in chlorobenzene in the presence of 0.2 equivalents of a heteropoly acid, and anthraquinone, anthrone, and xanthone were obtained in good yield. At the same time, an intermolecular Friedel?Crafts acylation and decarboxylation reaction were observed in this experiment. CSIRO 2007.

Synthesis of annulated arenes and heteroarenes involving lewis acid-mediated regioselective annulation of unsymmetrical 1,2-(Diaryl/ diheteroarylmethine)dipivalates

A ZnBr2-mediated regioselective annulation of unsymmetrical 1,2-diarylmethinedipivalates in DCM at room temperature led to the formation of annulated arenes and heteroarenes. The annulation of the dipivalate proceeds through the intermediacy of

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere via N-H imines as an intramolecular directing group

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere was developed starting from carbonitriles and Grignard reagents via N-H imine intermediates. The present process is characterized by the following two-step sequence in a one-pot manner: (1) addition of Grignard reagents to carbonitriles to form N-H imines and (2) benzylic C-H oxygenation (C=O bond formation) triggered by 1,5-hydrogen atom transfer with transient iminyl copper species.