57785-86-1

Basic information

• Product Name: 2-Pyridinol, 4-methylbenzenesulfonate (ester)
• CAS NO: 57785-86-1
• Molecular Formula: C12H11NO3S
• Molecular Weight: 249.29
• Mol File: 57785-86-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-Pyridinol, 4-methylbenzenesulfonate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinol, 4-methylbenzenesulfonate (ester)(57785-86-1)
• EPA Substance Registry System: 2-Pyridinol, 4-methylbenzenesulfonate (ester)(57785-86-1)

Safety Data

• Hazardous Substances Data: 57785-86-1(Hazardous Substances Data)

Upstream product

• 142-08-5 2-Pyridone 
• 98-59-9 p-toluenesulfonyl chloride 
• 29637-85-2 1-tosyl-pyridin-2(1H)-one 
• 142-08-5 2-hydroxypyridin 
• 4124-41-8 p-toluenesulfonylanhydride 
• 657-84-1 sodium tosylate 
• 504-29-0 2-aminopyridine 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 101-82-6 2-Benzylpyridine 
• 109293-39-2 2-acetylbenzoic acid 2-methyl-4-(3-trifluoromethylphenyl)-semicarbazone 
• 21298-55-5 3-(2-pyridyl)thiophene 
• 4253-81-0 2-(2-nitrophenyl)pyridine 
• 51263-32-2 N-2-pyridylcaprolactam 
• 3419-91-8 N-(2-pyridyl)indole 
• 349574-30-7 3-methyl-N-(pyridin-2-yl)butanamide 
• 86847-59-8 2-(pivaloylamino)pyridine 
• 6631-37-4 2-(phenylamino)pyridine 
• 1285695-10-4 (4-(2-hydroxyphenyl)piperazin-1-yl)(pyridin-2-yl)methanone 
• 172138-95-3 N,N'-((1S,2S)-cyclohexane-1,2-diyl)dipicolinamide 
• 1090354-52-1 N-(3-phenylprop-2-yn-1-yl)picolinamide 
• 1158179-21-5 N-(1'-hydroxy-1'-phenylpropan-2'-yl)-N-methylpicolinamide 
• 1285695-11-5 N-((1'R,2'R)-1'-hydroxy-1'-phenylpropan-2'-yl)-N-methylpicolinamide 

Relevant articles and documents

Highly efficient Diels-Alder cycloadditions of 2-pyridones with bulky N-sulfonyl substituent

The rearrangement of N-sulfonyl pyridones to the corresponding O-sulfonyl pyridinols during cycloaddition can be greatly retarded by introduction of steric congestion on either the pyridone ring or the sulfonyl group. Hence, significantly improved yields

Coupling of C(sp3)-H bonds with C(sp2)-O electrophiles: mild, general and selective

Herein is reported the mild and general coupling of amine/ether C(sp3)-H bonds with various kinds of C(sp2)-O electrophiles with high selectivity and efficiency. Valuable allylic/benzylic amines are generated in moderate to excellent yields. The utility of this transformation is demonstrated by a broad substrate scope (>50 examples), good functional group tolerance and facile product modification.

A Novel Convenient Synthesis of Pyridinyl and Quinolinyl Triflates and Tosylates via One-Pot Diazotization of Aminopyridines and Aminoquinolines in Solution

The first effective and simple method for the direct one-pot transformation of 2-, 3-, and 4-aminopyridines, 2,6-diaminopyridines, and 2-aminoquinoline into the corresponding pyridinyl and quinolinyl trifluoromethanesulfonates and tosylates in solvents was developed. The procedure involves diazotization of the heterocyclic amines with sodium nitrite in mixed hexane-DMSO or hexane-DMF solutions in the presence of trifluoromethanesulfonic acid or p-toluenesulfonic acid.