577991-16-3Relevant academic research and scientific papers
A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude
Choi, Yongseok,George, Clifford,Comin, Maria J.,Barchi Jr., Joseph J.,Kim, Hak Sung,Jacobson, Kenneth A.,Balzarini, Jan,Mitsuya, Hiroaki,Boyer, Paul L.,Hughes, Stephen H.,Marquez, Victor E.
, p. 3292 - 3299 (2007/10/03)
The synthesis and biological evaluation of a bicyclo[3.1.0]hexene nucleoside designed as a conformational mimic of the anti-HIV agent stavudine (1, D4T) is described. The unsaturated methanocarbocyclic pseudosugar of N-MCD4T (2) was constructed from an io
