578-07-4

Basic information

• Product Name: 4-AMINOACRIDINE
• Synonyms: 4-AMINOACRIDINE;4-acridinamine;4-amino-acridin;4-aminoakridin;Acridin-4-amine;Acridine-5-amine;acridin-4-ylamine
• CAS NO: 578-07-4
• Molecular Formula: C₁₃H₁₀N₂
• Molecular Weight: 194.23
• Mol File: 578-07-4.mol

Chemical Properties

• Melting Point: 108°C
• Boiling Point: 320.68°C (rough estimate)
• Flash Point: 237.2 °C
• Appearance: /
• Density: 1.1579 (rough estimate)
• Vapor Pressure: 2.95E-07mmHg at 25°C
• Refractive Index: 1.5014 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: 13.6mg/L(24 oC)
• CAS DataBase Reference: 4-AMINOACRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINOACRIDINE(578-07-4)
• EPA Substance Registry System: 4-AMINOACRIDINE(578-07-4)

Safety Data

• Hazardous Substances Data: 578-07-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H10N2/c14-11-6-3-5-10-8-9-4-1-2-7-12(9)15-13(10)11/h1-8H,14H2

Upstream product

• 4261-62-5 4-nitro-9(10H)-acridinone 
• 28948-44-9 2-(2-nitro-anilino)-benzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 88-74-4 2-nitro-aniline 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 18123-20-1 4-hydroxyacridine 
• 7462-74-0 2-bromo-2-methylpropanamide 
• 71-41-0 pentan-1-ol 
• 81104-13-4 4-aminoacridin-9(10H)-one 
• 42955-73-7 4-Nitroacridine 

Downstream Products

• 102025-55-8 N-acridin-4-yl-glycin-ethyl ester 
• 18123-20-1 4-hydroxyacridine 
• 136496-10-1 Hexanedioic acid bis-acridin-4-ylamide 
• 136496-11-2 Heptanedioic acid bis-acridin-4-ylamide 
• 136496-12-3 Decanedioic acid bis-acridin-4-ylamide 

Relevant articles and documents

1,2-Dihydro-1-hydroxy-2,3,1-benzodiazaborine Bearing an Acridine Moiety as a Circular Dichroism Probe for Determination of Absolute Configuration of Mono-Alcohols

A new chiral probe molecule for mono-alcohols is developed by using 1,2-dihydro-1-hydroxy-2,3,1-benzodiazaborine (DAB) bearing an acridine moiety 1. In the presence of mono-alcohols, DAB 1 forms borate 2 by boronic ester formation, followed by coordination of the acridine moiety to the boron atom. Borate 2 has a chiral center on the boron atom and works as a stereodynamic circular dichroism (CD) probe molecule for chiral mono-alcohols based on the π–π interaction between the acridine moiety and the carbon–carbon unsaturated moiety on mono-alcohols.

PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES

A process of converting a hydroxy heteroaromatic compound to an arylamine, comprising the steps of : 1) treating a salt of a hydroxy heteroaromatic compound with an alkylating agent; and 2) treating the reaction mixture with a Smiles solvent system and raising the temperature of the reaction mixture; and a compound made according to the above process.

Process for converting hydroxy heteroaromatics to arylamines

A process of converting a hydroxy heteroaromatic compound to an arylamine, comprising the steps of: (1) treating a salt of a hydroxy heteroaromatic compound with an alkylating agent; and (2) treating the reaction mixture with a Smiles solvent system and raising the temperature of the reaction mixture; and A compound made according to the above process.

Direct Conversion of Hydroxy Aromatic Compounds to Heteroarylamines via a One-Pot Smiles Rearrangement Procedure

8-Hydroxyquino line (9) was converted to 8-aminequinoline (10) in a one-pot procedure involving alkylation with 2-bromo-2-methylpropionamide (2) followed by Smiles rearrangement and hydrolysis, in 41% yield. The scope and limitations of this new procedure were explored with additional hydroxyquinolines.