57864-70-7

Basic information

• Product Name: 2H-1,2,4-Benzothiadiazine, 3-(4-methoxyphenyl)-, 1,1-dioxide
• CAS NO: 57864-70-7
• Molecular Formula: C14H12N2O3S
• Molecular Weight: 288.327
• Mol File: 57864-70-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2H-1,2,4-Benzothiadiazine, 3-(4-methoxyphenyl)-, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2,4-Benzothiadiazine, 3-(4-methoxyphenyl)-, 1,1-dioxide(57864-70-7)
• EPA Substance Registry System: 2H-1,2,4-Benzothiadiazine, 3-(4-methoxyphenyl)-, 1,1-dioxide(57864-70-7)

Safety Data

• Hazardous Substances Data: 57864-70-7(Hazardous Substances Data)

Upstream product

• 100-09-4 4-methoxybenzoic acid 
• 3306-62-5 2-AMINOBENZENESULFONAMIDE 
• 123-11-5 4-methoxy-benzaldehyde 
• 77925-51-0 2-(N,N-diethylaminosulfonyl)nitrobenzene 
• 874-90-8 4-methoxybenzonitrile 
• 61666-75-9 2-(4-metoxyphenyl)benzo[d][1,3]dithiole 
• 104-93-8 p-methylanizole 
• 2393-23-9 4-methoxy-benzylamine 
• 105-13-5 4-Methoxybenzyl alcohol 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 104-01-8 4-Methoxyphenylacetic acid 

Relevant articles and documents

Aerobic primary and secondary amine oxidation cascade by a copper amine oxidase inspired catalyst

Herein, we report a bioinspired catalytic system for the one-pot cascade oxidation of a native primary amine and anin situgenerated non-native secondary amine. The catalyst consists of ano-quinone cofactor phd (1,10-phenanthroline-5,6-dione) and a copper ion and operates under ambient air conditions. Quinazolin-4(3H)-ones, which are common pharmacophores present in numerous pharmaceuticals and bioactive compounds, were synthesized in high yields. A detailed kinetic and mechanistic study elucidates the role of the catalyst in the multi-step oxidative cascade reaction.

Metal-free sequential dual oxidative amination of C(sp3)–H bonds: A direct approach to benzothiadiazine 1,1-dioxide derivatives

An efficient and metal-free Di-tert-butyl peroxide (DTBP)-promoted dual oxidative amination annulation of 2-amino arylsulfonamide with methylarene has been developed. This protocol provides straightforward access to benzothiadiazine 1,1-dioxide derivatives without using prefunctionalized substrates in good to excellent yields with good functional group tolerance.

Facile synthesis of 2H-1,2,4-benzothiadiazine 1,1-dioxides promoted by Sml2

2H-1,2,4-Benzothiadiazine 1,1-dioxides are prepared in good yields via reductive cyclisation of N,N-diethyl-o-nitrobenzenesulfonamides with appropriate nitriles promoted by Sml2 under mild and neutral conditions.