57948-55-7Relevant articles and documents
APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS. PART 7. SYNTHESIS AND METALLATION OF 4-METHOXYPICOLIN- AND 2-METHOXYISONICOTIN-ANILIDES. A USEFUL METHOD FOR PREPARATION OF 2,3,4-TRISUBSTITUTED PYRIDINES
Epsztajn, Jan,Bieniek, Adam,Plotka, Mieczyslaw W.,Suwald, Krzysztof
, p. 7469 - 7476 (2007/10/02)
The synthesis and metallation of 4-methoxypicolin- and 2-methoxyisonicotin-anilides as a way of regiospecific transformation of picolinic and isonicotinic acids into 2,3,4-trisubstituted pyridines, is described.The resulted C-alkylated derivatives underwent smooth acid - catalysed conversion into the corresponding pyridones.