126798-20-7

Upstream product

• 124-41-4 sodium methylate 
• 126798-22-9 4-nitropicolinanilide 
• 29082-91-5 4-methoxypyridine-2-carboxylic acid 
• 62-53-3 aniline 
• 57948-55-7 4-Nitro-1-oxy-pyridine-2-carbonyl chloride 
• 14933-78-9 2-carboxy-4-nitropyridine-1-oxide 
• 824-40-8 2-pyridinecarboxylic acid N-oxide 
• 98-98-6 2-Picolinic acid 

Downstream Products

• 126798-25-2 7-methoxy-1-(p-methoxyphenyl)-furo<3,4-b>pyridine-3(1H)-one 
• 1027904-21-7 3-Benzylsulfanyl-4-methoxy-pyridine-2-carboxylic acid phenylamide 
• 1575753-43-3 C₁₇H₁₉N₃O₃ 
• 126798-30-9 1-(p-methoxyphenyl)-furo<3,4-b>pyridine-3,7(1H,4H)-dione 
• 126798-29-6 1,3-dimethyl-4-pyridone-2-carboxanilide 
• 126798-23-0 3-methyl-4-methoxypicolinanilide 

Relevant academic research and scientific papers

Copper-catalyzed carboxamide-directed ortho amination of anilines with alkylamines at room temperature

In this report, a highly efficient method for the room temperature installation of alkyl amino motifs onto the ortho position of anilines via Cu-catalyzed carboxamide-directed amination with alkylamines is described. This method offers a practical solution for the rapid synthesis of complex arylamines from simple starting materials and enables new planning strategies for the construction of arylamine-containing pharmacophores. A single electron transfer (SET)-mediated mechanism is proposed.

APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS. PART 7. SYNTHESIS AND METALLATION OF 4-METHOXYPICOLIN- AND 2-METHOXYISONICOTIN-ANILIDES. A USEFUL METHOD FOR PREPARATION OF 2,3,4-TRISUBSTITUTED PYRIDINES

The synthesis and metallation of 4-methoxypicolin- and 2-methoxyisonicotin-anilides as a way of regiospecific transformation of picolinic and isonicotinic acids into 2,3,4-trisubstituted pyridines, is described.The resulted C-alkylated derivatives underwent smooth acid - catalysed conversion into the corresponding pyridones.