57963-08-3

Basic information

• Product Name: 2-AMINO-5,6-DIMETHYLPYRIDINE
• Synonyms: 2-AMINO-5,6-DIMETHYLPYRIDINE;5,6-DIMETHYL-PYRIDIN-2-YLAMINE;2-Pyridinamine,5,6-dimethyl-;2-Amino-5,6-dimenthylpyridine;(5,6-dimethyl-2-pyridyl)amine;5,6-dimethylpyridin-2-amine;6-Amino-2,3-dimethylpyridine;5,6-Dimethylpyridin-2-amine, 2-Amino-5,6-dimethylpyridine, 6-Amino-2,3-lutidine
• CAS NO: 57963-08-3
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Product Categories: Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Pyridines;Amines;Aromatics;Heterocycles
• Mol File: 57963-08-3.mol

Chemical Properties

• Boiling Point: 231.8 °C at 760 mmHg
• Flash Point: 116.9 °C
• Appearance: Light Yellow Low-Melting Solid
• Density: 1.039 g/cm³
• Vapor Pressure: 0.0611mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: Chloroform, Dichloromethane
• CAS DataBase Reference: 2-AMINO-5,6-DIMETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5,6-DIMETHYLPYRIDINE(57963-08-3)
• EPA Substance Registry System: 2-AMINO-5,6-DIMETHYLPYRIDINE(57963-08-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-37/39-39
• Hazardous Substances Data: 57963-08-3(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Low-Melting Solid

InChI:InChI=1/C7H10N2/c1-5-3-4-7(8)9-6(5)2/h3-4H,1-2H3,(H2,8,9)

Upstream product

• 583-61-9 2,3-Lutidine 
• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 823-96-1 Trimethylboroxine 
• 13061-96-6 dihydroxy-methyl-borane 
• 22710-07-2 2,3-dimethylpyridine 1-oxide 

Downstream Products

• 161091-49-2 2-amino-3-bromo-5,6-dimethylpyridine 
• 1428879-16-6 C₂₀H₁₇N₃O₂S 
• 1446790-62-0 6-((1R,2S)-2-amino-cyclohexylamino)-4-(5,6-dimethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide 
• 1446792-19-3 tert-butyl (1S,2R)-2-(6-carbamoyl-5-(4,6-dimethylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate 
• 1446819-69-7 6-((1R,2S)-2-aminocyclohexylamino)-4-(4,6-dimethylpyridin-2-ylamino)pyridazine-3-carboxamide 2,2,2-trifluoroacetate 
• 1620997-93-4 5-bromo-N-(5,6-dimethylpyridin-2-yl)phthalamic acid tert-butyl ester 
• 1620997-02-5 5-bromo-N-(5,6-dimethylpyridin-2-yl)phthalamic acid 
• 1620998-47-1 N-(5,6-dimethylpyridin-2-yl)-4,5-bis-trifluoromethylphthalamic acid methyl ester 
• 1446791-96-3 tert-butyl (1S,2R)-2-(6-carbamoyl-5-(5,6-dimethylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate 

Relevant articles and documents

AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS

Provided herein are compounds of Formula (I) and Formula (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS

There is provided compounds of formula (I) wherein W is an optionally substituted aryl or heteroaryl group, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15- lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthases.

A series of substituted 2-aminopyridines was prepared and evaluated as inhibitors of human nitric oxide synthases (NOS). 4,6-Disubstitution enhanced both potency and specificity for the inducible NOS with the most potent compound having an IC50 of 28 nM.

Syntheses of 1,5,6-trimethyl-2-aminoimidazo[4,5-b]pyridine and 3,5,6-trimethyl-2-aminoimidazo[4,5-b]pyridine

Two potential mutagens found in food, 1,5,6-trimethyl-2-aminoimidazo[4,5-b]pyridine and 3,5,6-trimethyl-2-aminoimidazo[4,5-b]pyridine, are synthesized.