5797-02-4

Basic information

• Product Name: acetyl benzyl disulfide
• Synonyms: acetyl benzyl disulfide
• CAS NO: 5797-02-4
• Molecular Formula: C₉H₁₀OS₂
• Molecular Weight: 0
• Mol File: 5797-02-4.mol

Chemical Properties

• Boiling Point: 315.8°Cat760mmHg
• Flash Point: 136.5°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0.000428mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: acetyl benzyl disulfide(CAS DataBase Reference)
• NIST Chemistry Reference: acetyl benzyl disulfide(5797-02-4)
• EPA Substance Registry System: acetyl benzyl disulfide(5797-02-4)

Safety Data

• Hazardous Substances Data: 5797-02-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10OS2/c1-8(10)12-11-7-9-5-3-2-4-6-9/h2-6H,7H2,1H3

Upstream product

• 6405-82-9 acetyl-chloro-sulfane 
• 100-53-8 phenylmethanethiol 
• 6313-36-6 benzyl thiosulphate 
• 507-09-5 tiolacetic acid 
• 16302-98-0 petivericin 
• 100-44-7 benzyl chloride 
• 10387-40-3 potassium thioacetate 

Downstream Products

• 16601-17-5 phenyl phenylmethyl disulfide 
• 77764-68-2 1-(benzyldisulfanyl)-4-chlorobenzene 
• 831-91-4 Benzyl phenyl sulfide 
• 26905-24-8 1-benzylsulfanyl-4-methoxy-benzene 
• 16601-19-7 1-(benzyl)-2-(4-methylphenyl)disulfide 

Relevant articles and documents

Acyl Selenyl Sulfides as the Precursors for Reactive Sulfur Species (Hydrogen Sulfide, Polysulfide, and Selenyl Sulfide)

Persulfides are receiving increased attention due to their links to hydrogen sulfide (H2S) and hydrogen polysulfide (H2Sn). Their close analogues selenyl sulfides (RSeSHs), however, have limited literature precedent, and their reactivity and possible role in biology are largely unknown. Here, we devised an acyl selenyl sulfide template to study RSeSH chemistry. Their stability and reactivity toward amines/thiols were studied. These compounds can produce H2S or H2S2 under different conditions, suggesting that RSeSHs are possible intermediates.

Aryl-alkyl asymmetric persulfate compound, and synthesis method and application thereof

The invention discloses an aryl-alkyl asymmetric persulfate compound shown as a formula (3) and a synthesis method thereof. Arylboronic acid shown as a formula (I) and R2SSCOR3 shown as a formula (2) are used as reaction raw materials; under the effects of metal copper catalysts, reaction is performed to obtain the aryl-alkyl asymmetric persulfate compound. The method has the advantages that the reaction conditions are mild; the raw materials are low in cost and easy to obtain; the reaction operation is simple; the yield is higher; cheap metal is used as catalysts in the reaction process; economy and practicability are realized; the environment-friendly performance is achieved; reaction substrates can be easily prepared; after the reaction amplification, the reaction efficiency is high. The prepared aryl-alkyl asymmetric persulfate compound shown as the formula (3) and prepared by the method can be used for further synthesizing potential medicine compounds containing C-S bonds, such as benzyl (phenyl) thioether and benzyl (4-methoxy phenyl) thioether. The aryl-alkyl asymmetric persulfate compound and the synthesis method provided by the invention have the advantages of wide application prospects and practical value.

Generation of reactive oxygen species by a persulfide (BnSSH)

Hydropersulfides (RSxSH) have been implicated as important intermediates in the cell-killing action of the anticancer natural products leinamycin and varacin. It has been suggested that persulfides can mediate the conversion of molecular oxygen to reactive oxygen species (O2 .-, H2O2, and HO.). Here, experiments with synthetic benzyl hydrodisulfide (BnSSH) provide direct evidence that persulfides readily decompose to produce reactive oxygen species under physiologically relevant conditions.

A facile synthesis of acetyl alkyl disulfides

The preparation of acetyl alkyl disulfides 2, which are key intermediates for the synthesis of alkyl hydrodisulfides 1, from disulfides is described. Disulfides are oxidized to sulfinothioic acid S-esters (thiosulfinates) which thioalkylate thioacetic aci