57987-14-1 Usage
Uses
Used in Pharmaceutical Industry:
Nicotinic Acid-13C1 is used as a therapeutic agent for the treatment of ischemia in animal models. The administration of Nicotinic Acid-13C1 has been shown to significantly reduce the size of infarction and improve functional recovery, indicating its potential in treating conditions related to reduced blood flow.
Used in Neurological Applications:
Nicotinic Acid-13C1 is used as a potential treatment for traumatic brain injury. Current findings suggest that Nicotinic Acid-13C1 may have therapeutic potential in this area, offering a new avenue for research and development in the treatment of brain injuries.
Used in Nutritional Supplements:
As a form of vitamin B3, Nicotinic Acid-13C1 is used as a dietary supplement to ensure adequate intake of this essential nutrient, which is vital for maintaining normal body function and overall health.
Check Digit Verification of cas no
The CAS Registry Mumber 57987-14-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,8 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 57987-14:
(7*5)+(6*7)+(5*9)+(4*8)+(3*7)+(2*1)+(1*4)=181
181 % 10 = 1
So 57987-14-1 is a valid CAS Registry Number.
57987-14-1Relevant academic research and scientific papers
Meinert,Nunez,Byerrum
, p. 893 - 896,894,895 (1978)
Nicotinic acid, an intermediate in the pyridine nucleotide cycle, was labeled with 13C at the 7 position. The reaction of CuCN-13C (prepared from NaCN-13C) with 3-bromopyridine, followed by hydrolysis to the acid and purification by ion exchange chromatography, gave an overall yield of 72% nicotinic acid 7-13C. This greater than 3-fold increase in yield over previous methods is the result of in situ hydrolysis of the nitrile intermediate.
Palladium-mediated carboxylation of aryl halides (triflates) or benzyl halides using [13C]/[11C]carbon monoxide with tetrabutylammonium hydroxide or trimethylphenylammonium hydroxide
Karimi, Farhad,Langstroem, Bengt
, p. 2256 - 2259 (2007/10/03)
[Carbonyl-11C]carboxylic acids were synthesised using palladium-mediated reaction of [11C]carbon monoxide with aryl halides/triflates and benzyl halides in combination with either tetrabutylammonium hydroxide or trimethylphenylammoni
