57987-14-1 Usage
Uses
Isotope labelled analogue of Nicotinic Acid (N429250), also known as vitamin B3, is an essential nutrient that must be obtained from a dietary source in order for normal body function. The administration of Nicotinic Acid in animal models of ischemia was shown to significantly reduce the size of infarction and improve functional recovery. Current findings suggest that nicotinic acid may have therapeutic potential for the treatment of traumatic brain injury.
Check Digit Verification of cas no
The CAS Registry Mumber 57987-14-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,8 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 57987-14:
(7*5)+(6*7)+(5*9)+(4*8)+(3*7)+(2*1)+(1*4)=181
181 % 10 = 1
So 57987-14-1 is a valid CAS Registry Number.
57987-14-1Relevant articles and documents
The synthesis of nicotinic acid-7-13C
Meinert,Nunez,Byerrum
, p. 893 - 896,894,895 (1978)
Nicotinic acid, an intermediate in the pyridine nucleotide cycle, was labeled with 13C at the 7 position. The reaction of CuCN-13C (prepared from NaCN-13C) with 3-bromopyridine, followed by hydrolysis to the acid and purification by ion exchange chromatography, gave an overall yield of 72% nicotinic acid 7-13C. This greater than 3-fold increase in yield over previous methods is the result of in situ hydrolysis of the nitrile intermediate.
