58061-99-7Relevant academic research and scientific papers
Isolation, Chemical Modification, and Anticancer Activity of Major Metabolites of the Lichen Parmotrema mesotropum
Mallavadhani, Uppuluri Venkata,Tirupathamma, Reddy Srilakshmi,Sagarika,Ramakrishna, Sistla
, p. 825 - 831 (2019/11/13)
Extensive chromatographic purification of the chloroform–methanol (1:1) extract of the lichen Parmotrema mesotropum led to the isolation of methyl hematommate (1), methyl-2,4-dihydroxy-3,6-dimethylbenzoate (2), orcinol (3), and atranorin (4). The two majo
A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate
Ohsawa, Kosuke,Yoshida, Masahito,Doi, Takayuki
, p. 3438 - 3444 (2013/06/26)
A silver trifluoromethanesulfonate (AgOTf)-promoted direct and mild formylation of benzenes has been developed. The reaction utilizing dichloromethyl methyl ether (Cl2CHOMe) and AgOTf powerfully formylated various substituted benzenes under temperature conditions as low as -78 C without losing the protecting groups on the phenolic hydroxyl group.
Total synthesis of racemosol and de-O-methylracemosol, potent cyclooxygenase (COX) inhibitors and antimalarial agents
Sae-Lao, Patcharaporn,Kittakoop, Prasat,Rajviroongit, Shuleewan
, p. 345 - 348 (2007/10/03)
The total synthesis of antimalarial and cyclooxygenase inhibitors, racemosol and de-O-methylracemosol, is described. The key steps involved the lateral lithiation reaction of ortho-methyl tolulate and the pyran formation via a tandem demethylation-cycliza
