4707-46-4

Basic information

• Product Name: 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID
• Synonyms: 3-METHYLORSELLINIC ACID;3,6-DIMETHYL-2,4-DIHYDROXYBENZOIC ACID;2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID;Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-;2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID 99+%;2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID F;2,4-Dihydroxy-3,6-dimethylbenzoic acid for synthesis
• CAS NO: 4707-46-4
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.17
• Mol File: 4707-46-4.mol

Chemical Properties

• Melting Point: 186-189°C
• Boiling Point: 407.4°C at 760 mmHg
• Flash Point: 214.3°C
• Appearance: /
• Density: 1.386g/cm³
• Vapor Pressure: 2.29E-07mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Store below +30°C.
• CAS DataBase Reference: 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID(4707-46-4)
• EPA Substance Registry System: 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID(4707-46-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-36/37
• WGK Germany: WGK 2 water endangering
• Hazardous Substances Data: 4707-46-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dihydroxy-3,6-dimethylbenzoic acid is used as a pharmaceutical ingredient for its antioxidant and anti-inflammatory effects. It contributes to the development of treatments for various diseases by mitigating oxidative stress and inflammation, which are common pathological factors in many conditions.
Used as a Food Additive:
In the food industry, 2,4-Dihydroxy-3,6-dimethylbenzoic acid serves as a flavoring agent, enhancing the taste and aroma of food products while also providing health benefits due to its antioxidant properties. This helps in preserving the quality and extending the shelf life of food items.
Used in Skincare Products:
2,4-Dihydroxy-3,6-dimethylbenzoic acid is utilized as a key component in skincare products for its antioxidant properties. It helps protect the skin from environmental stressors and promotes skin health by reducing inflammation and signs of aging, making it a valuable ingredient in creams, lotions, and other topical formulations.
Used in Antioxidant Applications:
Due to its potent antioxidant capabilities, 2,4-Dihydroxy-3,6-dimethylbenzoic acid is employed in various applications where neutralizing free radicals and preventing oxidative damage are crucial. This includes uses in dietary supplements, health products, and even industrial applications where oxidative stability is required.

InChI:InChI=1/C9H10O4/c1-4-3-6(10)5(2)8(11)7(4)9(12)13/h3,10-11H,1-2H3,(H,12,13)

Upstream product

• 17636-16-7 barbatic acid 
• 32837-48-2 3-methyl-heptane-2,4,6-trione 
• 124-38-9 carbon dioxide 
• 436-32-8 diffractaic acid 
• 20372-89-8 4-(2,4-dihydroxy-3,6-dimethylbenzoyloxy)-2-hydroxy-3,6-dimethylbenzoic acid 
• 75-65-0 tert-butyl alcohol 
• 56410-32-3 4-benzyloxy-2-hydroxy-3,6-dimethylbenzoic acid 
• 69336-17-0 methyl 4-(benzyloxy)-2-hydroxy-3,6-dimethylbenzoate 
• 4707-47-5 2,4-dihydroxy-3,6-dimethyl-benzoic acid methyl ester 
• 6161-74-6 methyl barbatolate 
• 529-50-0 barbatolic acid 
• 34883-14-2 2,4-dihydroxy-3,6-dimethylbenzaldehyde 
• 31581-32-5 ethyl 2,4-dihydroxy-3,6-dimethylbenzoate 
• 186581-53-3 diazomethane 

Downstream Products

• 31581-32-5 ethyl 2,4-dihydroxy-3,6-dimethylbenzoate 
• 488-87-9 2,5-dimethyl-1,3-benzenediol 
• 5038-46-0 methyl 4-(2,4-dihydroxy-3,6-dimethylbenzoyloxy)-2-hydroxy-3,6-dimethylbenzoate 
• 4707-47-5 2,4-dihydroxy-3,6-dimethyl-benzoic acid methyl ester 
• 17636-16-7 barbatic acid 
• 56410-30-1 benzyl 2,4-dihydroxy-3,6-dimethylbenzoate 
• 58061-99-7 methyl 2,4-dimethoxy-3,6-dimethylbenzoate 

Relevant articles and documents

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The invention provides a method for synthesizing 2,4-dihydroxy-3,6-dimethyl methyl benzoate (synthetic oak moss) by using 4-O-demethylated barbatic acid, and relates to the technical field of chemicalsynthesis. The technical scheme comprises: hydrolyzing 4-O-demethylated barbatic acid into 2,4-dihydroxy-3,6-dimethyl benzoic acid by adopting an acid hydrolysis or alkali hydrolysis method; carryingout a methyl esterification reaction with a methylation reagent by using 2,4-dihydroxy-3,6-dimethyl benzoic acid as a substrate; and treating after the reaction is finished so as to obtain 2,4-dihydroxy-3,6-dimethyl methyl benzoate (synthetic oak moss). According to the invention, the synthetic oak moss is synthesized by using the new intermediate through two-step synthesis, so that the synthesisprocess is simplified.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

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Chemical study on Garhwal Himalayan Lichen: Usnea emidotteries

Usnea species are medicinally important, so we take unexplored species, Usnea emidotteris. Seven components 2-hydroxy-3-methoxy-4, 6-dimethyl ethyl benzoate, 2, 4-dihydro-xy-3, 6-dimethyl ethyl benzoate, 2-hydroxy-4-methoxy-3, 6-dimethylbezoic acid, usnic

Hypoalectorialic acid and conechinocarpic acid, two new benzyl esters from lichens

The benzyl esters hypoalectorialic acid [6-(2′,4′-dihydroxy-3′,6′-dimethylbenzoyloxymethyl)-2,4- dihydroxy-3-methylbenzoic acid] (5) and conechinocarpic acid [1′,4′-dihydroxy-6′-methoxy-3′-oxo-1′,3′- dihydroisobenzofuran-5′-ylmethyl 2-hydroxy-4-methoxy-3,6-dimethylbenzoate] (7) have been isolated from the lichens Hypotrachyna hypoalectorialica and Relicina samoensis respectively. The structure of the compounds (5) and (7) followed from a combination of spectroscopic and chemical data.

LICHEN ACIDS, PLANT GROWTH INHIBITORS FROM USNEA LONGISSIMA

Eight components, depsides and orcinol derivatives which exhibit growth-inhibitory activity against lettuce seedlings were isolated from Usnea longissima and identified from their physicochemical data.Key Word Index - Usnea longissima; depside; β-orcinol;

TERT-BUTANOLYSIS OF LICHEN DEPSIDES

The scope and limit of the tert-butanolysis of 12 lichen depsides is described.Neither 2-O-methylated nor 2-O-acylated compounds are cleaved by heating with tert-butanol.Key Word Index - Depsides: tert-butanolysis.