4707-47-5Relevant articles and documents
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Fujii,Osumi
, (1936)
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Two new glycosides from Dianella ensifolia (L.) DC
Fan, Miao-Yin,Liu, Bing-Rui,Yang, Fan,Zhang, Pu-Zhao
, p. 18 - 20 (2021/11/11)
The Dianella genus includes approximately 20 species in all over the world. So far, only the chemical constituents of the lipophilic extract from Dianella ensifolia have been investigated. However, there have been no reports of its aqueous extract. In thi
Compositional variation of atranorin-related components of lichen Myelochroa leucotyliza dependent on extraction solvent and their quantitative analysis by qHNMR
Ojha, Manju,Kil, Yun-Seo,Youn, Ui Joung,Ok, Young Jun,Choi, Hyukjae,Nam, Joo-Won
, p. 1067 - 1073 (2021/04/05)
Introduction: Quantitative nuclear magnetic resonance (qNMR) is one of the effective and reliable quantification tools for natural product research. Myelochroa leucotyliza belongs to the genus Myelochroa, a common foliose lichen genus found in the Korean Peninsula, and has not been quantitatively analysed using NMR. Previous chemical studies on M. leucotyliza have been limited to the main components by traditional thin-layer chromatography (TLC) experiments. Objective: We explored the stability of atranorin, a major component of M. leucotyliza, in methanol and acetone using NMR and characterised the changes in the chemical profiles of the lichen extracts in methanol and acetone using qNMR. Methodology: Atranorin transformation in the presence of methanol was analysed using time-dependent proton (1H)-NMR analysis (600 MHz NMR spectrometer). A 1H qNMR (qHNMR) method was established using dimethyl sulfone as the internal standard for quantifying the selected components isolated from M. leucotyliza. Homogenous mixtures of the samples were dissolved in deuterated chloroform. Results: Time-dependent 1H-NMR experiments revealed that atranorin (5) from lichen M. leucotyliza decomposed into atraric acid (1) and methyl haemmatommate (2) in methanol. Four components were identified from M. leucotyliza: 1, 2, usnic acid (4), and 5, and their respective contents were determined using qHNMR. The percentages (w/w) of 1, 2, and 4 in the methanol extract were calculated as 5.66%, 0.69%, and 0.90%, while those of 1, 4, and 5 in the acetone extract were 1.70%, 1.68%, and 19.11%, respectively. Conclusion: We used qHNMR to effectively analyse quantitative compositional variations in two different M. leucotyliza extracts and reliably determined the chemical conversion of the unstable compound atranorin.
Method for aromatizing synthetic oak moss
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Paragraph 0021; 0023-0028, (2019/01/14)
The invention provides a method for aromatizing synthetic an oak moss. The method comprises the following steps: adding chlorinated 2,5dimethyl-dihydro-methyl resorcylate into a solvent acetonitrile for aromatization reaction; then carrying out cooling crystallization to obtain a coarse product of the synthetic oak moss. Compared with the prior art, the method for aromatizing the oak moss, disclosed by the invention, has the following advantages: firstly, the by-product sodium chloride produced by the reaction can be directly filtered; secondly, reactive water can be recycled; thirdly, when the aromatization reaction is carried out, the reaction is not drastic because the reaction occurs in the acetonitrile solvent, and the generated hydrogen chloride is easy to recover; fourthly, an aftertreatment process is simple and the purity of the produced crude product reaches 98 percent or above. Therefore, the method provides an improved process method for the synthetic oak moss, which is environmentally friendly and energy saving and can be used for industrial production.
