58065-65-9Relevant academic research and scientific papers
Iodine-Promoted Synthesis of Thioamides from 1,2-Dibenzylsulfane and Difurfuryl Disulfide
Chen, Sihai,Li, You,Chen, Jinyang,Xu, Xinhua,Su, Lebin,Tang, Zhi,Au, Chak-Tong,Qiu, Renhua
, p. 2339 - 2344 (2016)
Thioamides can be generated at 100 °C in high yield through the reaction of 1,2-dibenzyldisulfane with difurfuryldisulfide using iodine as oxidant and DMSO as solvent. The protocol is metal- and additive-free, providing a convenient and economical way for the synthesis of various kinds of thioamides under mild conditions.
Microwave-assisted synthesis of thioamides with elemental sulfur
Milen, Matyas,Abranyi-Balogh, Peter,Dancso, Andras,Keglevich, Gyoergy
experimental part, p. 33 - 41 (2012/07/01)
Thioamides are prepared in moderate-to-good yields from the benzylamines or benzylamine derivatives by treatment with elemental sulfur under microwave and solvent-free conditions at 170.C in 15 min.
Lawesson's reagent for direct thionation of hydroxamic acids: Substituent effects on LR reactivity
Przychodzen, Witold
, p. 676 - 684 (2007/10/03)
To explore the generality and scope of direct thionation of hydroxamic acids (HAs), the reaction of various structurally diverse HAs with Lawesson's reagent was investigated. The yield of thiohydroxamic acid (THAs) is poor when HAs possess bulky acyl and/or N-substituents, acidic α-hydrogen atoms, or an N-phenyl ring. THAs yields were correlated with Brown sigma parameter. The relative rates of two subsequent processes kT2 and kR2 were also measured. Correlation was also found for methine proton chemical shifts of N-isopropyl benzothiohydroxamic acids.
