58122-03-5

Basic information

• Product Name: 3-(3-CHLOROPHENYL)PROPIOPHENONE
• Synonyms: 3-(3-CHLOROPHENYL)PROPIOPHENONE
• CAS NO: 58122-03-5
• Molecular Formula: C₁₅H₁₃ClO
• Molecular Weight: 244.72
• Mol File: 58122-03-5.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 381.3°C at 760 mmHg
• Flash Point: 213°C
• Appearance: /
• Density: 1.164g/cm³
• Vapor Pressure: 5.14E-06mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 3-(3-CHLOROPHENYL)PROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-CHLOROPHENYL)PROPIOPHENONE(58122-03-5)
• EPA Substance Registry System: 3-(3-CHLOROPHENYL)PROPIOPHENONE(58122-03-5)

Safety Data

• Hazardous Substances Data: 58122-03-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H13ClO/c16-14-8-4-5-12(11-14)9-10-15(17)13-6-2-1-3-7-13/h1-8,11H,9-10H2

Upstream product

• 22966-13-8 3-(3-chlorophenyl)-1-phenylprop-2-en-1-one 
• 98-85-1 1-Phenylethanol 
• 873-63-2 m-chlorobenzyl alcohol 
• 2039-85-2 3-Chlorostyrene 
• 65-85-0 benzoic acid 
• 100-52-7 benzaldehyde 
• 587-04-2 m-Chlorobenzaldehyde 
• 98-86-2 acetophenone 
• 123558-73-6 3-(3-Chloro-phenyl)-2-methanesulfonyl-1-phenyl-propan-1-one 
• 123558-69-0 (Z)-3-(3-Chloro-phenyl)-2-methanesulfonyl-1-phenyl-propenone 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 1180676-64-5 ethyl 5-(3-chlorophenyl)-3-phenylpent-2-enoate 
• 1180676-63-4 ethyl 5-(3-chlorophenyl)-3-phenylpent-2-enoate 
• 22966-13-8 (2E)-3-(3-chlorophenyl)-1-phenylprop-2-en-1-one 

Relevant articles and documents

Nickel-catalyzed α-alkylation of ketones with benzyl alcohols

We reported an efficient method for α-alkylation of ketones with benzyl alcohols using the pyridine-bridged pincer-type N-heterocyclic carbenes nickel complexes as catalysts. A wide range of ketones and benzyl alcohols were efficiently converted into various alkylated products in moderate to high yields. In addition, these nickel complexes were also successfully applied for the synthesis of a wide range of quinoline derivatives.

Neutral-eosin Y-catalyzed regioselective hydroacylation of aryl alkenes under visible-light irradiation

Styrene derivatives were hydroacylated with exclusive anti-Markovnikov selectivity by using neutral eosin Y as a direct hydrogen-atom-transfer (HAT) catalyst under visible-light irradiation. Aldehydes and styrenes with various substituents were tolerated (>20 examples), giving the corresponding products in moderate to high yields. The key acyl radical intermediate was generated from a direct HAT process induced by photoexcited eosin Y. Subsequent addition to styrenes and a reverse HAT process generated the ketone products.

Chemoselective Hydrosilylation of the α,β-Site Double Bond in α,β- And α,β,γ,δ-Unsaturated Ketones Catalyzed by Macrosteric Borane Promoted by Hexafluoro-2-propanol

The B(C6F5)3-catalyzed chemoselective hydrosilylation of α,β- and α,β,γ,δ-unsaturated ketones into the corresponding non-symmetric ketones in mild reaction conditions is developed. Nearly 55 substrates including those bearing reducible functional groups such as alkynyl, alkenyl, cyano, and aromatic heterocycles are chemoselectively hydrosilylated in good to excellent yields. Isotope-labeling studies revealed that hexafluoro-2-propanol also served as a hydrogen source in the process.