582310-30-3

Upstream product

• 1693-23-8 (5-Methoxy-2-nitrophenyl)-(4-fluorophenyl)amine 
• 108-95-2 phenol 
• 371-40-4 4-fluoroaniline 
• 1545-85-3 [(E)-(4-flourophenyl)diazenyl]phenol 
• 51788-91-1 (E)-1-(4-fluorophenyl)-2-(4-methoxyphenyl)diazene 

Downstream Products

• 582310-31-4 6-Methoxy-1-(4-fluorophenyl)-2-(3-thienyl)-1H-benzimidazole 
• 582310-37-0 6-Methoxy-1-(4-fluorophenyl)-2-(3-pyridinyl)-1H-benzimidazole 

Relevant academic research and scientific papers

The selective synthesis ofN-arylbenzene-1,2-diamines or 1-arylbenzimidazoles by irradiating 4-methoxy-4′-substituted-azobenzenes in different solvents

The solvent-controllable photoreaction of 4-methoxyazobenzenes to afford 1-aryl-1H-benzimidazoles orN-arylbenzene-1,2-diamines has been studied. The irradiation of 4-methoxyazobenzenes in DMF containing 0.5 M hydrochloric acid providedN2-aryl-4-methoxybenzene-1,2-diamines as the major product, while irradiation in acetal containing 0.16 M hydrochloric acid led to 1-aryl-6-methoxy-2-methyl-1H-benzimidazoles as the major product. A possible reaction mechanism explaining the selectivity was also discussed.

1-Phenyl-2-heteroaryl-substituted benzimdazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives

New benzimidazole derivatives are described, their production and their use for the production of pharmaceutical agents for treatment and prevention of diseases that are associated with a microglia activation and T-cell-mediated immunological diseases, as