58249-83-5

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(Benzoyloxymethyl)benzoic acid is used as a synthetic intermediate for the preparation of various pharmaceutical compounds. It can be converted into different derivatives, which have potential applications in the medical field.
Used in Chemical Synthesis:
In the chemical industry, 2-(Benzoyloxymethyl)benzoic acid is used as a starting material for the synthesis of various organic compounds, including:
1. 2-(Benzoyloxymethyl)benzoyl chloride (BMBC): 2-(BENZOYLOXYMETHYL)BENZOIC ACID is synthesized by reacting 2-(Benzoyloxymethyl)benzoic acid with oxalyl chloride. BMBC is an important intermediate in the production of other organic compounds.
2. Dimethyl 2-(benzoyloxymethyl)benzoylphosphonate: 2-(BENZOYLOXYMETHYL)BENZOIC ACID is prepared by treating BMBC with trimethyl phosphite. It has potential applications in the development of new materials and chemicals.
3. 2-Benzoyloxymethylbenzoic acid 4-nitrophenyl ester: This ester is formed by reacting BMBC with 4-nitrophenol. It can be used as a building block for the synthesis of more complex molecules.
4. 2-[2-(Benzoyloxymethyl)benzamido]acetamide: 2-(BENZOYLOXYMETHYL)BENZOIC ACID is synthesized by treating BMBC with glycinamide, followed by the addition of PCl3. It has potential applications in the development of new pharmaceuticals and other chemical products.

InChI:InChI=1/C15H12O4/c16-14(17)13-9-5-4-8-12(13)10-19-15(18)11-6-2-1-3-7-11/h1-9H,10H2,(H,16,17)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1430334-90-9 C₂₀H₂₁NO₃ 
• 1430334-89-6 C₁₈H₁₇NO₃ 
• 6754-94-5 N-Carbamoylmethyl-2-methyl-benzamide 
• 58249-85-7 Benzoic acid 2-p-tolylcarbamoyl-benzyl ester 
• 58249-89-1 2-methyl-N-(4-methylphenyl)-benzamide 
• 58249-87-9 2-benzoyloxymethyl benzoic acid chloride 
• 58249-84-6 Benzoic acid 2-(carbamoylmethyl-carbamoyl)-benzyl ester 

Relevant academic research and scientific papers

Aziridine ring-containing chiral ligands as highly efficient catalysts in asymmetric synthesis

Enantiomerically pure bidentate heteroorganic ligands built on an achiral skeleton containing hydroxyl and aziridine moieties as nucleophilic centers, capable of binding various organometallic reagents, have proven to be highly efficient catalysts in the enantioselective addition of diethylzinc and phenylethynylzinc to aryl and alkyl aldehydes to give the desired chiral products in high chemical yields (up to 90%) and with ees of up to 95%. The influence of the stereogenic center located in the carbon atom in the aziridine moiety on the stereochemical course of the reaction is reported.

Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases

Derivatives of general chemical formula L(I) and (IV) are used in the topical treatment of diseases of the epithelial tissues, like psoriasis (epidermis) and ulcerative colitis L(lower intestine). These compounds display a high efficacy when administered for example by epicuaneous route in the case of dermatological illnesses like psoriasis, atopic dermatitis and other similar affections, or when administered by oral or rectal route in the case of diseases of the epithelia of the lower intestine like the ulcerative colitis and Crohn's disease.

3,5-Diphenyl-1H-1,2,4-triazoles pharmaceutical compositions and uses

3,5-diphenyl-1H-1,2,4-triazoles with contragestational activity of the following formula STR1 wherein R may be located on one or the other of the two adjacent nitrogen atoms and may represent hydrogen or a group R5 CO-- wherein R5 is an aliphatic saturated or unsaturated hydrocarbyl containing from 1 to 20 carbon atoms, R1, R2 and R3, each independently are selected from hydrogen, lower alkyl and lower alkoxy or R2 and R3 together may represent a methylenedioxy group, and R4 is an aliphatic saturated or unsaturated hydrocarbyl group of from 1 to 20 carbons, with the proviso that when R is hydrogen or an R5 CO-- group wherein R5 contains 4 or less carbon atoms, R4 must contain 5 or more carbons. These compounds have proven to be highly effective in terminating pregnancy in several animal species after a single parenteral injection.