58537-98-7Relevant articles and documents
Preorganized Macrocyclic Receptors Featuring endo-Carboxylic Acid Groups. Host Synthesis and Inclusion Compounds with Alcohol and Amine Guests
Weber, Edwin,Haase, Reinhard,Pollex, Rolf,Czugler, Matyas
, p. 274 - 283 (2007/10/03)
The synthesis and characterization of four new macrocyclic host compounds 1-4 having modified diphenylmethane units as bridging elements and two endo-orientated carboxylic acid groups attached to aromatic building blocks are described. The complexation pr
Macrocyclic polyether carboxylic acids
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, (2008/06/13)
A series of novel, macrocyclic polyether compounds. The macrocycles have a 21-membered ring, containing six oxygen atoms, and they have a carboxy group (or a salt thereof) directed towards the interior of the ring. Administration of the compounds of the invention to ruminant animals (e.g. cattle and sheep) modifies their digestive fermentation processes such that the volatile fatty acids produced in the rumen contain a higher proportion of propionates rather than acetates, thereby increasing the efficiency of feed utilization in said ruminant animals. Additionally, the compounds of the invention show antibacterial activity in vitro against certain gram-positive microorganisms.